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Characterization of Biomaterials with NMR

Published online by Cambridge University Press:  21 February 2011

Leoncio Garrido ,
Bettina Pfleiderer ,
Jerome L. Ackerman  and
John Moore
Leoncio Garrido
Affiliation:
NMR Center, Massachusetts General Hospital and Harvard Medical School, 149 13th St., Charlestown, MA 02129.
Bettina Pfleiderer
Affiliation:
NMR Center, Massachusetts General Hospital and Harvard Medical School, 149 13th St., Charlestown, MA 02129.
Jerome L. Ackerman
Affiliation:
NMR Center, Massachusetts General Hospital and Harvard Medical School, 149 13th St., Charlestown, MA 02129.
John Moore
Affiliation:
NMR Center, Massachusetts General Hospital and Harvard Medical School, 149 13th St., Charlestown, MA 02129.
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Abstract

Silicone based biomaterials are characterized with NMR. Bulk spin-lattice (T1) and spin-spin (T2) relaxation times are measured in polydimethylsiloxane (PDMS) model networks and various types of implants. The T2 results seem to indicate that crosslink densities of these biomaterials are lower than those of the PDMS model networks studied. 1H chemical shift NMR imaging techniques are developed to investigate the aging (e.g., migration of free polymer, rupture due to mechanical stress, etc.) of biomaterials in vivo.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 217: Symposium U – Advanced Tomographic Imaging Methods for the Analysis of Materials , 1990 , 49
Copyright
Copyright © Materials Research Society 1991

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References

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