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Cartilage: Biomimetic Study of the Extracellular Matrix

  • Chinedu I. Anyaeji (a1), Peter J. Basser (a1) and Ferenc Horkay (a1)

Abstract

Cartilage is a complex biological tissue that exhibits gel-like behavior. Its primary biological function is providing compressive resistance to external loading and nearly frictionless lubrication of joints. In this study, we model cartilage extracellular matrix using a biomimetic system. We demonstrate that poly(vinyl) alcohol (PVA) hydrogels are robust biomaterials exhibiting mechanical and swelling properties similar to that of cartilage extracellular matrix. A comparison is made between the macroscopic behavior of PVA gels and literature data reported for cartilage.

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Keywords

Cartilage: Biomimetic Study of the Extracellular Matrix

  • Chinedu I. Anyaeji (a1), Peter J. Basser (a1) and Ferenc Horkay (a1)

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