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Additive Manufacturing Technologies for the 3D Fabrication of Biocompatible and Biodegradable Photopolymers

Published online by Cambridge University Press:  31 January 2011

Christian Heller ,
Martin Schwentenwein ,
Franz Varga ,
Jürgen Stampfl  and
Robert Liska
Christian Heller
Affiliation:
christian.heller@ias.tuwien.ac.at, Vienna University of Technology, Institute of Applied Synthetic Chemistry, Vienna, Austria
Martin Schwentenwein
Affiliation:
martin.schwentenwein@ias.tuwien.ac.at, Vienna University of Technology, Institute of Applied Synthetic Chemistry, Vienna, Austria, Austria
Franz Varga
Affiliation:
franz.varga@osteologie.at, Ludwig Boltzmann Institute of Osteology, Hanusch Hospital Vienna, Vienna, Austria, Austria
Jürgen Stampfl
Affiliation:
jstampfl@pop.tuwien.ac.at, TU Wien, Inst. Materials Science and TEchnology, Favoritenstr. 9, Wien, 1040, Austria
Robert Liska
Affiliation:
robert.liska@tuwien.ac.at, Vienna University of Technology, Institute of Applied Synthetic Chemistry, Vienna, Austria, Austria
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Abstract

High molecular weight vinyl esters and carbonates based on oligo(ethylene glycol), oligomeric fatty acids and poly(hexamethylene carbonate), as alternatives for potentially cytotoxic acrylate based monomers have been structured by Additive Manufacturing Technologies (AMTs) like Microstereolithography (μ-SLA), Digital Light Processing (DLP) and Two-Photon Induced Photopolymerization (TPIP). With these techniques feature resolutions down to 10 μm (μ-SLA and DLP) or even 200 nm (TPIP) can be obtained. This new class of monomers exhibits LC50 values for cytotoxicity up to two orders of magnitude lower than acrylate references. Beside a high reactivity of the resin, the shrinkage and the mechanical properties of the final part material are another essential parameter. Low molecular weight monomers are very reactive and lead to densely cross-linked materials which suffer from high shrinkage and strains within the cured material. Therefore, mixtures of high molecular weight vinyl esters/carbonates with low molecular weight crosslinkers have been evaluated regarding their photoreactivity and mechanical properties.

Keywords

photochemicalbiomateriallithography (deposition)
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1239: Symposium VV – Micro- and Nanoscale Processing of Biomaterials , 2009 , 1239-VV08-05
Copyright
Copyright © Materials Research Society 2010

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References

1 Leong, K. F. Cheah, C. M. and Chua, C. K. Biomaterials 24, 2363 (2003).Google Scholar
2 Liska, R. Stampfl, J. Varga, F. Gruber, H. Baudis, S. Heller, C. Schuster, M. Bergmeister, H. Weigel, G. and Dworak, C. (2009). 78pp. Application: WO 2009065162 A2Google Scholar
3 Heller, C. Schwentenwein, M. Varga, F. Ruessmueller, G. Stampfl, J. Liska, R. J. Polym. Sci., Part A: Polym. Chem., (2009), in printGoogle Scholar
4 Luegmayr, E. Varga, F. Frank, T. Roschger, P. Klaushofer, K. Bone 18, 591 (1996).Google Scholar
5 Varga, F. Rumpler, M. Luegmayr, E. Fratzl-Zelman, N., Glantschnig, H. Klaushofer, K. Calcif Tissue Int 61, 404 (1997).Google Scholar
6 Thaler, R. Karlic, H. Spitzer, S. Klaushofer, K. Varga, F. Apoptosis in print (2010).Google Scholar
7 Meza, J. M. Farias, M. C. M. Souza, R. M. d. and Riaño, L. J. C., Materials Research 10, 437 (2007).Google Scholar
8 Baudis, S. Heller, C. Liska, R. Stampfl, J. Bergmeister, H. and Weigel, G. J. Polym. Sci., Part A: Polym. Chem. 47, 2664 (2009).Google Scholar
9 Stampfl, J. Baudis, S. Heller, C. et al. , J. Micromech. Microeng. 18, 125014/1 (2008).Google Scholar
10 Pucher, N. Rosspeintner, A. Satzinger, V. Schmidt, V. Gescheidt, G. Stampfl, J. and Liska, R. Macromolecules (Washington, DC, U. S.) 42, 6519 (2009).Google Scholar
11 Ullrich, G. Ganster, B. Salz, U. Moszner, N. and Liska, R. J. Polym. Sci., Part A: Polym. Chem. 44, 1686 (2006).Google Scholar