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VUV-photon Induced Formation of Hydrophilic and Hydrophobic Micro Domains Structure on Intraocular Lens Surface for Blocking after Cataract

Published online by Cambridge University Press:  01 February 2011

Yuji Sato
Affiliation:
yuzzy99@yahoo.co.jp, Tokyo Institute of Technology, Innovative Research Initiatives, P.O.Box I3-26 2-12-1 o-okayama meguro-ku, tokyo, 152-8552, Japan, 81-3-5734-2860
Kenji Kawai
Affiliation:
k-kawai@is.icc.u-tokai.ac.jp, Tokai University, Kanagawa, 259-1292, Japan
Mikio Sasoh
Affiliation:
sasoh@clin.medic.mie-u.ac.jp, Mie University, Mie, N/A, Japan
Hiroaki Ozaki
Affiliation:
hozaki@fukuoka-u.ac.jp, Fukuoka University, Fukuoka, N/A, Japan
Takeo Ohki
Affiliation:
ohgi@clin.med.tokushima-u.ac.jp, University of Tokushima, Tokushima, N/A, Japan
Hiroshi Shiota
Affiliation:
shiota@clin.med.tokushima-u.ac.jp, University of Tokushima, Tokushima, N/A, Japan
Masataka Murahara
Affiliation:
mmurahara@yahoo.co.jp, Innovative Research Initiatives, Tokyo, N/A, Japan
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Abstract

A micro domain structure, which hydrophilic and hydrophobic groups were arrayed alternately, was formed on the surface of an intraocular lens [IOL] by using ultra violet rays [VUV]. With this technique, the IOL that is free from fibrin has been developed. In order to substitute the hydrophilic groups in matrix-form on the surface, an ArF laser light was then irradiated on the hydrophobic surface in the presence of water for the −OH groups, through the 50-micrometer dot-patterned reticle. With this selective photochemical surface modification, the hydrophilic and hydrophobic groups were arrayed alternately on the sample surface. The modified IOL was soaked in 0.1-wt % fibrin solutions, and the fibrin-sticking rate was measured by using an infrared spectroscopy [FT-IR]. It results that the absorption coefficient of amide band reached to 0.0006, decreasing to one-six of non-treatment sample's.

Type
Research Article
Copyright
Copyright © Materials Research Society 2008

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VUV-photon Induced Formation of Hydrophilic and Hydrophobic Micro Domains Structure on Intraocular Lens Surface for Blocking after Cataract
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VUV-photon Induced Formation of Hydrophilic and Hydrophobic Micro Domains Structure on Intraocular Lens Surface for Blocking after Cataract
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