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Effect of Experimental Conditions on the Chemical Composition of Hydroxyapatite Synthesized by Chemical Precipitation

Published online by Cambridge University Press:  28 January 2018

Jorge López-Cuevas ,
Juan C. Rendón-Angeles ,
José L. Rodríguez-Galicia  and
Carlos A. Gutiérrez-Chavarría
Jorge López-Cuevas*
Affiliation:
CINVESTAV-IPN, Unidad Saltillo, Calle Industria Metalúrgica No. 1062, Parque Industrial Saltillo - Ramos Arizpe, Ramos Arizpe, Coahuila, México, CP25900
Juan C. Rendón-Angeles
Affiliation:
CINVESTAV-IPN, Unidad Saltillo, Calle Industria Metalúrgica No. 1062, Parque Industrial Saltillo - Ramos Arizpe, Ramos Arizpe, Coahuila, México, CP25900
José L. Rodríguez-Galicia
Affiliation:
CINVESTAV-IPN, Unidad Saltillo, Calle Industria Metalúrgica No. 1062, Parque Industrial Saltillo - Ramos Arizpe, Ramos Arizpe, Coahuila, México, CP25900
Carlos A. Gutiérrez-Chavarría
Affiliation:
CINVESTAV-IPN, Unidad Saltillo, Calle Industria Metalúrgica No. 1062, Parque Industrial Saltillo - Ramos Arizpe, Ramos Arizpe, Coahuila, México, CP25900
*
*Corresponding author; Tel. +52 844 4389600; E-mail address: jorge.lopez@cinvestav.edu.mx
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Abstract

Hydroxyapatite [HAp, Ca5(PO4)3(OH)] was synthesized by chemical precipitation, using H3PO4 and Ca(OH)2 as chemical precursors. The precursors were slowly mixed in suitable proportions aiming to obtain Ca/P molar ratios of 1.5, 1.67 or 2.0 in the reacting suspension. This was followed by 21.5 h of aging. Both reaction and aging stages were carried out under an atmosphere of still ambient air and under continuous stirring, either at room temperature, 60 or 90 °C. The precipitates were characterized by ICP-AES and XRD. The results suggested that the most suitable Ca/P molar ratio for the production of pure phase HAp is Ca/P = 1.67, as long as the initial Ca(OH)2 particle size and/or the suspension pH are carefully controlled, especially when the synthesis is carried out above room temperature.

Keywords

biomaterialchemical synthesisbone
Type
Articles
Information
MRS Advances , Volume 2 , Issue 61: International Materials Research Congress XXV , 2017 , pp. 3851 - 3857
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Copyright
Copyright © Materials Research Society 2018 

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References

LeGeros, R.Z., Bautista, C., Styner, P., LeGeros, J.P., Vijiayaraghavan, T.V., Retino, M. and Valdecanas, A., in Bioceramics 8, edited by Wilson, J., Hench, L.L. and Greenspan, D. (Pergamon/Elsevier, UK, 1995) pp. 81–87.Google Scholar
Rathje, W., Pflanz, Z.. Bodenkunde 12, 121–128 (1939).CrossRefGoogle Scholar
Berndt, C.C., Haddad, G.N., Farmer, A.J.D. and Gross, K.A., Mater. Forum 14, 161–173 (1990).Google Scholar
Webster, A.V., Cooper, J.J., Hampson, C.J. and Cubbon, R.C.P., Br. Ceram. Trans. J. 86, 91–98 (1987).Google Scholar
Suwa, Y., Banno, H., Mizuno, M. and Saito, H., J. Ceram. Soc. Jpn. 101, 642–647 (1993).Google Scholar
Young, R.A. and Holcomb, D.W., Calcif. Tissue Int. 34, S17–S32 (1982).Google Scholar
Brown, W.E. and Chow, L.C., in Cements Research Progress, edited by Brown, P.W. (American Ceramic Society, Westerville, OH, USA, 1986) pp. 351–379.Google Scholar
Acevedo-Dávila, J.L., López-Cuevas, J., Vargas-Gutiérrez, G., Rendón-Angeles, J.C. and Méndez-Nonell, J., Bol. Soc. Esp. Ceram. Vidrio 46, 225–231 (2007).Google Scholar
Vargas, G., López, J., Acevedo, J.L., Romero, J., Méndez, J. and Méndez, M., Phosphorus Res. Bull. 10, 250–255 (1999).Google Scholar