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Single Cell Force Measurements and Cell Adhesion

Published online by Cambridge University Press:  14 March 2018

Torsten Mueller*
JPK Instruments AG, Berlin Germany
Tanja Neumann
JPK Instruments AG, Berlin Germany


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This short review describes the relevance of cell adhesion in cell biology. Starting with a short overview of the force range of adhesion related biological events and the current biophysical techniques for investigating these events, it will conclude with a description of the use of single cell force spectroscopy for quantifying mechanical properties such as stiffness, surface tension, and bond disruption forces.

Research Article
Copyright © Microscopy Society of America 2008


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