Hostname: page-component-8448b6f56d-t5pn6 Total loading time: 0 Render date: 2024-04-18T05:23:02.062Z Has data issue: false hasContentIssue false
  • English
  • Français

Structural Rearrangements in R432A Variant of AAV2 Affect Genome Packaging

Published online by Cambridge University Press:  25 July 2016

Lauren M. Drouin ,
Bridget Lins ,
Mandy Janssen ,
Antonette Bennett ,
Paul R. Chipman ,
Robert McKenna ,
Weijun Chen ,
Nicholas Muzyczka ,
Giovanni Cardone  and
Timothy S. Baker
...Show all authors
Lauren M. Drouin
Affiliation:
Department of Biochemistry & Molecular Biology, Center for Structural Biology, The McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA
Bridget Lins
Affiliation:
Department of Biochemistry & Molecular Biology, Center for Structural Biology, The McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA
Mandy Janssen
Affiliation:
Department of Chemistry and Biochemistry, and Division of Biological Sciences, University of California—San Diego, San Diego, California, USA
Antonette Bennett
Affiliation:
Department of Biochemistry & Molecular Biology, Center for Structural Biology, The McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA
Paul R. Chipman
Affiliation:
Department of Biochemistry & Molecular Biology, Center for Structural Biology, The McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA
Robert McKenna
Affiliation:
Department of Biochemistry & Molecular Biology, Center for Structural Biology, The McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA
Weijun Chen
Affiliation:
Department of Molecular Genetics and Microbiology, University of Florida Genetics Institute, College of Medicine, University of Florida, Gainesville, FL, USA
Nicholas Muzyczka
Affiliation:
Department of Molecular Genetics and Microbiology, University of Florida Genetics Institute, College of Medicine, University of Florida, Gainesville, FL, USA
Giovanni Cardone
Affiliation:
Department of Chemistry and Biochemistry, and Division of Biological Sciences, University of California—San Diego, San Diego, California, USA
Timothy S. Baker
Affiliation:
Department of Chemistry and Biochemistry, and Division of Biological Sciences, University of California—San Diego, San Diego, California, USA
Mavis Agbandje-McKenna
Affiliation:
Department of Biochemistry & Molecular Biology, Center for Structural Biology, The McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA

Abstract

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Abstract
Information
Microscopy and Microanalysis , Volume 22 , Supplement S3: Proceedings of Microscopy & Microanalysis 2016 , July 2016 , pp. 1134 - 1135
Copyright
© Microscopy Society of America 2016 

References

References:

[1] Asokan, A, Scaffer, DV & Samulski, RJ Mol Ther 20 (2012) 699–708.Google Scholar
[2] Chapman, M & Agbandje-McKenna, M in “Parvoviruses” (ed. Ker, JR et al, Edward Arnold Ltd, NY.Google Scholar
[3] Grimm, D., et al., Gene Ther 6 (1999) 1322–1330.Google Scholar
[4] Wu, P., et al., J Virol 74 (2000) 8634–8647.Google Scholar
[5] Bleker, S, Pawlitta, M & Kleinschmidt, JA J Virol 80 (2006) 810–820.CrossRefGoogle Scholar
[6] Warrington, , et al., J Virol 78 (2004) 6595–6609.CrossRefGoogle Scholar
[7] Emsley, P., et al., Acta Cryst. D 66 (2010) 486–501.CrossRefGoogle Scholar
[8] Kronenberg, S., et al., J. Virol. 79 (2005) 5296–5303.CrossRefGoogle Scholar
[9] Nam, H.J., et al., J. Virol. 81 (2007) 12260–12271.CrossRefGoogle Scholar
[10] Funding provided by NIH P01 HL51811, R01 AI1081961, R-37 GM033050, Training Grant T32-GM008799, support from the University of California San Diego, and the Agouron Foundation to establish the cryoTEM facilities used in this study.Google Scholar