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Structural Investigation of Epididymal Microvasculature and Its Relation to Telocytes and Immune Cells in Camel

Part of: Micrographia Collection

Published online by Cambridge University Press:  15 July 2020

Manal T. Hussein  and
Fatma M. Abdel-Maksoud Open the ORCID record for Fatma M. Abdel-Maksoud [Opens in a new window]
Manal T. Hussein*
Affiliation:
Department of Anatomy and Histology, Faculty of Veterinary Medicine, Assiut University, Assiut71526, Egypt
Fatma M. Abdel-Maksoud
Affiliation:
Department of Anatomy and Histology, Faculty of Veterinary Medicine, Assiut University, Assiut71526, Egypt
*
*Author for correspondence: Manal T. Hussein, E-mail: manaltawfik22@gmail.com
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Abstract

The vascular and perivascular cells, including telocytes (TCs) and immune cells, play an important role in male fertility. The current study intended to describe in detail the microvascular structures harboring special regulatory devices in addition to the interstitial cellular components of the one-humped camel epididymis. The samples were collected from 10 clinically healthy mature camels (Camelus dromedarius). The distribution and characteristics of TCs, peripheral blood vessels of the epididymis, and immune cells were investigated using the light, immunohistochemistry, immunofluorescence, and transmission electron microscopy analyses. Frequent occlusive or throttle arterioles were demonstrated in the epididymal interstitium and their tunica media consisted of glomus cells. In addition, some vein walls consisted of one or two layers of glomus cells. TCs, fibroblasts, muscle cells, and tunica media of the blood vessels, that present in the loose connective tissue surrounding the intertubular interstitium of camel epididymis, showed a positive reaction with vimentin. The endothelium of blood vessels and veins showed positive immunoreactivity for CD34 and vascular endothelial growth factor (VEGF). Furthermore, VEGF, CD34, and S100 proteins were expressed in dendritic cells (DCs) as well as TCs. The current data suggest the involvement of DCs and TCs in angiogenesis and a possible role for the interstitial components in creating an appropriate milieu for the full maturation of sperms.

Keywords

camelepididymisglomusspecial blood vesselstelocyte
Type
Micrographia
Information
Microscopy and Microanalysis , Volume 26 , Issue 5 , October 2020 , pp. 1024 - 1034
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Copyright
Copyright © Microscopy Society of America 2020

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