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Pulmonary Guardians and Special Regulatory Devices in the Lung of Nile Monitor Lizard (Varanus niloticus) with Special Attention to the Communication Between Telocyte, Pericyte, and Immune Cells

Part of: Micrographia Collection

Published online by Cambridge University Press:  27 December 2021

Dalia Mohamedien Open the ORCID record for Dalia Mohamedien [Opens in a new window]  and
Mahmoud Awad Open the ORCID record for Mahmoud Awad [Opens in a new window]
Dalia Mohamedien
Affiliation:
Department of Histology, Faculty of Veterinary Medicine, South Valley University, Qena83523, Egypt
Mahmoud Awad*
Affiliation:
Department of Histology, Faculty of Veterinary Medicine, South Valley University, Qena83523, Egypt
*
*Corresponding author: Mahmoud Awad, E-mail: awad.histology83@gmail.com
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Abstract

Monitor lizards are acclimatized to a variety of environments. Most of the monitor species are terrestrial, although there are arboreal and semiaquatic monitors. Such accommodation requires unique cellular structure and regulatory devices in various organs, particularly their lungs. This study aimed to report the pulmonary guardians and special regulatory devices that may guard and promote the function of the lungs of the Nile monitor lizards (Varanus niloticus). Specially structured vessels were recorded in the pulmonary tissue involving atypical glomus vessels, vessels with variable wall thickness, and a venule with specialized internal elastic membrane. Moreover, numerous lung resident guardians could be identified including both alveolar and interstitial macrophages, dendritic cells, mast cells, and B- and T-lymphocytes. Pericytes were demonstrated surrounding the capillary endothelium with a characteristic direct hetero-cellular junction with telocytes. Telocytes established a microenvironment through an indirect hetero-cellular junction with the interstitial macrophage, dendritic cells, and pneumocyte type II. Collectively, these data indicate a significant role played by the specially structured vessels and the resident immune cells in guarding the pulmonary tissue of the Nile monitor lizards and promoting its function. Telocytes are suggested to play a key role in angiogenesis and cellular communication to promote the function of the immune cells.

Keywords

atypical glomus vesseldendritic cellsinterstitial macrophage lymphocytepericytetelocyte
Type
Micrographia
Information
Microscopy and Microanalysis , Volume 28 , Issue 1 , February 2022 , pp. 281 - 287
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Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press on behalf of the Microscopy Society of America

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Footnotes

†

Current address: Department of Animal Physiology, Graduate School of Integrated Science for Life, Hiroshima University, Higashihiroshima 739-8528, Japan.

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