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A Novel Event-Based Active Pixel Sensor for Cryo-EM Electron Counting

Published online by Cambridge University Press:  30 July 2021

Benjamin Bammes  and
Robert Bilhorn
Benjamin Bammes
Affiliation:
Direct Electron LP, Pearland, Texas, United States
Robert Bilhorn
Affiliation:
Direct Electron LP, San Diego, California, United States

Abstract

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Type
Vendor Symposium
Information
Microscopy and Microanalysis , Volume 27 , Supplement S1 , August 2021 , pp. 1334 - 1336
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Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press on behalf of the Microscopy Society of America

References

Kühlbrandt, W. (2014). The Resolution Revolution. Science, 343: 1443-1444.CrossRefGoogle ScholarPubMed
Nogales, E. (2016). “The development of cryo-EM into a mainstream structural biology technique.” Nat Methods 13(1): 24-7.CrossRefGoogle ScholarPubMed
Renaud, J.P., Chari, A., Ciferri, C., Liu, W.T., Rémigy, H.W., Stark, H., & Wiesmann, C. (2018). “Cryo-EM in drug discovery: achievements, limitations and prospects.” Nat Rev Drug Discov 17(7): 471-92.CrossRefGoogle ScholarPubMed
Vinothkumar, K.R. & Henderson, R. (2016). “Single particle electron cryomicroscopy: trends, issues and future perspective.” Q Rev Biophys 49: e13.Google ScholarPubMed
Jin, L. (2009). Direct electron detection in transmission electron microscopy. University of California, San Diego.Google Scholar
McMullan, G., Clark, A.T., Turchetta, R., & Faruqi, A.R. (2009). Enhanced imaging in low dose electron microscopy using electron counting. Ultramicroscopy, 109: 1411-1416.CrossRefGoogle ScholarPubMed
Li, X., Zheng S.Q. Egami K., Agard D.A., & Cheng Y. (2013). Influence of electron dose rate on electron counting images recorded with the K2 camera. Journal of Structural Biology, 184: 251-260.Google ScholarPubMed
This material is based upon work supported by the U.S. Department of Energy, Office of Science, under Award Number DE-SC0020577.Google Scholar