Hostname: page-component-848d4c4894-xm8r8 Total loading time: 0 Render date: 2024-06-16T12:59:15.978Z Has data issue: false hasContentIssue false

Inhibition of bacterial binding through dysfunction of bacterial adhesion pili

Published online by Cambridge University Press:  30 July 2021

Matthew Doran
Affiliation:
Boston University School of Medicine, Allston, Massachusetts, United States
Esther Bullitt
Affiliation:
Boston University School of Medicine, United States

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
3D Structures: From Macromolecular Assemblies to Whole Cells (3DEM FIG)
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press on behalf of the Microscopy Society of America

References

Qadri, F., Svennerholm, A.-M., Faruque, A. S. G. & Sack, R. B. Enterotoxigenic Escherichia coli in developing countries: epidemiology, microbiology, clinical features, treatment, and prevention. Clin. Microbiol. Rev. 18, 465483 (2005).CrossRefGoogle ScholarPubMed
Shah, N., DuPont, H. L. & Ramsey, D. J. Global etiology of travelers’ diarrhea: systematic review from 1973 to the present. Am. J. Trop. Med. Hyg. 80, 609614 (2009).CrossRefGoogle ScholarPubMed
Checkley, W. et al. Multi-country analysis of the effects of diarrhoea on childhood stunting. Int. J. Epidemiol. 37, 816830 (2008).CrossRefGoogle ScholarPubMed
Satterwhite, T. K., Evans, D. G., DuPont, H. L. & Evans, D. J. Role of Escherichia coli colonisation factor antigen in acute diarrhoea. Lancet Lond. Engl. 2, 181184 (1978).Google ScholarPubMed
Sakellaris, H., Munson, G. P. & Scott, J. R. A conserved residue in the tip proteins of CS1 and CFA/I pili of enterotoxigenic Escherichia coli that is essential for adherence. Proc. Natl. Acad. Sci. U. S. A. 96, 1282812832 (1999).CrossRefGoogle ScholarPubMed
Zheng, W., Andersson, M., Mortezaei, N., Bullitt, E. & Egelman, E. Cryo-EM structure of the CFA/I pilus rod. IUCrJ 6, 815821 (2019).Google ScholarPubMed
Baker, J. L., Dahlberg, T., Bullitt, E. & Andersson, M. Impact of an alpha helix and a cysteine-cysteine disulfide bond on the resistance of bacterial adhesion pili to stress. bioRxiv 2021. 01.18.427124 (2021).Google Scholar
Brown, J. W. et al. A Role for Salivary Peptides in the Innate Defense Against Enterotoxigenic Escherichia coli. J. Infect. Dis. 217, 14351441 (2018).CrossRefGoogle ScholarPubMed
Zivanov, J. et al. New tools for automated high-resolution cryo-EM structure determination in RELION-3. eLife 7, e42166 (2018).Google ScholarPubMed
Desta, I. T., Porter, K. A., Xia, B., Kozakov, D. & Vajda, S. Performance and Its Limits in Rigid Body Protein-Protein Docking. Structure 28, 1071-1081.e3 (2020).CrossRefGoogle ScholarPubMed
Brewer, D., Hunter, H. & Lajoie, G. NMR studies of the antimicrobial salivary peptides histatin 3 and histatin 5 in aqueous and nonaqueous solutions. Biochem. Cell Biol. Biochim. Biol. Cell. 76, 247256 (1998).CrossRefGoogle ScholarPubMed