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Imaging Resin-Cast Osteocyte Lacuno-Canalicular System at Bone-Bioactive Glass Interface by Scanning Electron Microscopy

Published online by Cambridge University Press:  26 February 2010

Alejandro A. Gorustovich
Alejandro A. Gorustovich*
Affiliation:
Research Laboratory, National Atomic Energy Commission (CNEA-Reg. Noroeste) and National Research Council (CONICET), Salta, A4408FTV, Argentina
*
E-mail: agorustovich@gmail.com
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Abstract

The morphology of the osteocyte lacuno-canalicular system at the bone-biomaterial implant-interface has not been fully investigated. In this study, the resin-cast scanning electron microscopy technique was used, for the first time, to image the lacuno-canalicular network within neoformed bone around bioactive glass (BG) particles implanted in rat tibia bone marrow. The most salient finding was that the osteocyte canaliculi pass through the calcium-phosphorus layer formed at the bone-BG interface and reach the silica-rich layer of the reacted BG.

Keywords

resin-cast SEMosteocyteslacuno-canalicular systembioactive glass
Type
Biological Applications
Information
Microscopy and Microanalysis , Volume 16 , Issue 2 , April 2010 , pp. 132 - 136
Copyright
Copyright © Microscopy Society of America 2010

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