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Cryogenic Transmission Electron Microscopy (Cryo-TEM) Reveals Morphological Changes of Liposomal Doxorubicin during In Vitro Release

Published online by Cambridge University Press:  04 August 2017

Yong Wu ,
Peter Petrochenko ,
Francis C. Szoka ,
Soumyarwit Manna ,
Bonhye Koo ,
Nan Zheng ,
Wenlei Jiang  and
Jiwen Zheng
Yong Wu
Affiliation:
Division of Biology, Chemistry and Materials Science, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, Food and Drug Administration, Silver Spring, MD, United States
Peter Petrochenko
Affiliation:
Division of Biology, Chemistry and Materials Science, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, Food and Drug Administration, Silver Spring, MD, United States Office of Research Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD, United States
Francis C. Szoka
Affiliation:
School of Pharmacy, University of California, San Francisco, CA
Soumyarwit Manna
Affiliation:
Division of Biology, Chemistry and Materials Science, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, Food and Drug Administration, Silver Spring, MD, United States Office of Research Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD, United States
Bonhye Koo
Affiliation:
Division of Biology, Chemistry and Materials Science, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, Food and Drug Administration, Silver Spring, MD, United States Office of Research Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD, United States
Nan Zheng
Affiliation:
Office of Research Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD, United States
Wenlei Jiang
Affiliation:
Office of Research Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD, United States
Jiwen Zheng
Affiliation:
Division of Biology, Chemistry and Materials Science, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, Food and Drug Administration, Silver Spring, MD, United States

Abstract

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Type
Abstract
Information
Microscopy and Microanalysis , Volume 23 , Supplement S1: Proceedings of Microscopy & Microanalysis 2017 , July 2017 , pp. 1216 - 1217
Copyright
© Microscopy Society of America 2017 

References

[1] Wu, Y, et al, International Journal of Pharmaceutics 505 2016). p 167.CrossRefGoogle Scholar
[2] Wu, Y, et al, Microscopy and Microanalysis 20 2014). p 1348.CrossRefGoogle Scholar
[3] Wu, Y, et al, Microscopy and Microanalysis 20 2014). p 1228.Google Scholar