Skip to main content Accessibility help
×
Home

Soft laser-plasma X-ray source for differential absorption imaging of tracing elements in thin samples

  • L. A. GIZZI (a1), C.A. CECCHETTI (a1), M. GALIMBERTI (a1), D. GIULIETTI (a1) (a2), A. GIULIETTI (a1), P. KOESTER (a1), L. LABATE (a1) (a3), S. LAVILLE (a1) and P. TOMASSINI (a1)...

Abstract

The differential imaging technique is particularly suitable for the detection of small concentrations of contrasts agents for biological and medical applications in samples using X-ray radiography. In this paper, we present an application of this technique using a laser-plasma soft X-ray source combined with a bent crystal. Using a Fresnel plate as a test object, we were able to obtain spatial resolutions of the order of a few tens of microns. The use of our configuration to perform differential imaging of a test-sample at the L2 edge of Br at 1,596 eV is finally demonstrated.

Copyright

Corresponding author

Address correspondence and reprint requests to: L.A. Gizzi, IPCF, Intense Laser Irradiation Laboratory, CNR, Via Maruzzi 1 Pisa 56124, Italy. E-mail: la.gizzi@ipcf.cnr.it

References

Hide All

REFERENCES

Andersson, E., Hölzer, G., Förster, E., Grätz, M., Kiernan, L., Sjögren, A. & Svanberg, S. (2001). Coronary angiography using laserplasma sources: X-ray source efficiency and optimization of a bent crystal monochromator. J. Appl. Phys. 90, 3048.
Barbarics, E., Kronauge, J.F., Costello, C.E., Janoki, G.A., Holman, B.L., Davison, A. & Jones, A.G. (1994). In-Vivo Metabolism Of The Technetium Isonitrile Complex [Tc(2-Ethoxy-2-Methyl-1-Isocyanopropane)(6)](+). Nuclear Medicine And Biology 21, 583.
Dill, T., Dix, W.-R., Hamm, C.W., Jungz, M., Kupper, W., Lohmann, M., Reime, B. & Ventura, R. (1998). Intravenous coronary angiography with synchrotron radiation. Eur. J. Phys. 19, 499.
Giulietti, D. & Gizzi, L.A. (1998). X-ray emission from laser-produced plasmas. La Rivista del Nuovo Cimento 21, 1.
Labate, L., Galimberti, M., Giulietti, A., Giulietti, D., Gizzi, L.A., Numico, R., & Salvetti, A. (2001). Line spectroscopy with spatial resolution of laser-plasma X-ray emission. Laser and Part. Beams 19, 117.
Labate, L. et al. (2004). Ray-tracing simulations of an X-ray optics based upon a bent crystal for imaging using laser-plasma X-ray sources. Laser Part. Beams 22, 253259.
Marzi, S., Giulietti, A., Giulietti, D., Gizzi, L.A. & Salvetti, A. (2000). A High Brightness Laser-Plasma X-ray source at IFAM: Characterisation and applications. Laser and Part. Beams 18, 109.
Pikuz, T.A. et al. (2001). Laser Part. Beams 19, 285.
Sanchez del Rio, M. et al. (2001). Rev. Sci. Instrum. 72, 3291.
Suortti, P. & Thomlinson, W. (2003). Medical applications of synchrotron radiation. Phys. Med. Biol. 48, R1.
Tillman, C., Mercer, I. & Svanberg, S. (1996). Elemental biological imaging by differential absorption with laser-produced x-ray source. J. Opt. Soc. Am. B 13, 209.

Keywords

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed