Skip to main content Accessibility help
×
Home

Control of movements of the stomach and spiral intestine of Raja and Scyliorhinus

  • J. Z. Young (a1)

Abstract

The extrinsic nerves of the stomach of dogfish and skates regulate the frequency and amplitude of contraction by inhibition followed by rebounds. By contrast the nerves of the spiral intestine are excitatory.

Stimulation of the vagus nerve of the ray produced slight reduction in the amplitude of spontaneous contractions of the cardiac stomach. Much greater inhibition was produced by stimulation of the sympathetic nerves and was followed by large rebound contractions. These effects were imitated by adrenalin and serotonin which altered the frequency and amplitude of contraction in various ways. These actions were not blocked by either propranalol (1–5 × 10−5 M) or phentolamine (2 × 10−5 M) and indeed were often increased. The excitatory response to adrenalin was not blocked by TTX even after this had blocked the response to the nerve. Responses both to the nerve and adrenaline were blocked by trazodone. Acetyl choline caused some contraction of the stomach but only at high concentration.

Muscles of the spiral intestine of Raja or Scyliorhinus were activated by stimulation of their sympathetic nerves and by adrenalin. These responses were not blocked by phentolamine and only reduced by propranalol They were blocked by trazodone. The response to adrenalin continued after the nerve was blocked by TTX. Acetyl choline had very little effect on the spiral intestine.

The striking differences between the responses of the stomach and intestine are probably related to the fact that the plexus in the latter contains no nerve cells. The neurons in the stomach are therefore presumbly connected with the inhibition and large rebound contractions.

Copyright

References

Hide All
Al Yassiri, M. M., Ankier, S. I. & Bridges, P. K., 1981. Trazodone, a new antidepressant. Life of Science, 28, 24492458.
Andrews, P. L. R. & Grundy, D., 1981. The effect of stimulus characteristics on the rebound contraction in the gastric corpus. Journal of Physiology, 313, 2425P.
Babkin, B. P., Friedman, M. H. F. & Mackay-Sawyer, M. E., 1935. Vagal and sympathetic innervation of the stomach in the skate. Journal of the Biological Board of Canada, 1, 239250.
Bottazzi, F., 1902. Untersuchungen über das viscerale Nervensystem der Selachier. Zeitschrift für Biologie, 43, 372.
Brodin, E., Alumets, J., Håkanson, R., Leander, S., Sundler, F., 1981. Immunoreactive substance P in the chicken gut: distribution, development and possible functional significance. Cell and Tissue Research, 216, 455469.
Burnstock, G., 1975. Purinergic transmission. In Handbook of Psycho-pharmacology (ed. Iversen, et al. ), pp. 131194. Plenum Press.
Campbell, G., 1975. Inhibitory vagal innervation of the stomach in fish. Comparative Biochemistry and Physiology, 50 C, 169170.
Campbell, G. & Burnstock, G., 1968. Comparative physiology of gastrointestinal motility. In Handbook of Physiology, section 6, Alimentary Canal, vol. IV, Motility (ed. Code, C. F.), pp. 22132266. Washington, D.C.: American Physiological Society.
Euler, U. S. Von & Ostlund, E., 1957. Effects of certain biologically occurring substances on the isolated intestine offish. Acta physiologica scandinavica, 38, 364372.
Gershon, M. D., 1981. The enteric nervous system. Annual Review of Neuroscience, 4, 227272.
Leander, S., Hakanson, R., Rosell, S., Folkers, K., Sundler, F., Tornqvist, K., 1981. A specific substance P antagonist blocks smooth muscle contractions induced by non-cholinergic, non-adrenergic nerve stimulation. Nature, London, 294, 467469.
Moore, A. & Hiatt, R. B., 1967. Action of epinephrine on gastrointestinal motility in the spiny dogfish. Bulletin. Mount Desert Island Biological Laboratory, 7, 3233.
Müller, E. & Liljestrand, G., 1918. Anatomische u. experimentelle Untersuchungen über das autonomische Nervensystem der Elasmobranchien nebst Bemerkungen ü die Darmnerven bei den Amphibien u. Saugetieren. Archiv für Anatomie und Physiologie (Abteilung Anatomie), 1918, 137172.
Nicholls, J. V. V., 1933. The effect of temperature variations and of certain drugs upon the gastric motility of elasmobranch fishes. Contributions to Canadian Biology and Fisheries, 7, 449463.
Nicholls, J. V. V., 1934. Reaction of the smooth muscle of the gastro-intestinal tract of the skate to stimulation of autonomie nerves in isolated nerve muscle preparations. Journal of Physiology, 83, 5667.
Norberg, K. A. & Sjöqvist, F., 1966. New possibilities for adrenergic modulation of ganglionic transmission. Pharmacological Reviews, 18, 743751.
Young, J. Z., 1933. The autonomie nervous system of selachians. Quarterly Journal of Microscopical Science, 75, 571624.
Young, J. Z., 1980. Nervous control of stomach movements in dogfishes and rays. Journal of the Marine Biological Association of the United Kingdom, 60, 117.

Control of movements of the stomach and spiral intestine of Raja and Scyliorhinus

  • J. Z. Young (a1)

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed