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Treatment of naming in nonfluent aphasia through manipulation of intention and attention: A phase 1 comparison of two novel treatments

  • BRUCE CROSSON (a1) (a2), KATHERINE S. FABRIZIO (a2), FLORIS SINGLETARY (a3), M. ALLISON CATO (a2), CHRISTINA E. WIERENGA (a1) (a2), R. BRUCE PARKINSON (a2), MEGAN E. SHEROD (a1) (a2), ANNA BACON MOORE (a4) (a5), MARIBEL CIAMPITTI (a6), BETH HOLIWAY (a3), SUSAN LEON (a1), AMY RODRIGUEZ (a1), DIANE L. KENDALL (a1) (a7), ILANA F. LEVY (a2) and LESLIE J. GONZALEZ ROTHI (a1) (a7)...

Abstract

Twenty-three chronic nonfluent aphasia patients with moderate or severe word-finding impairments and 11 with profound word-finding impairments received two novel picture-naming treatments. The intention treatment initiated picture-naming trials with a complex left-hand movement and was designed to enhance right frontal participation during word retrieval. The attention treatment required patients to view visual stimuli for picture-naming trials in their left hemispace and was designed to enhance right posterior perisylvian participation during word retrieval. Because the intention treatment addressed action mechanisms and nonfluent aphasia reflects difficulty initiating or maintaining action (i.e., language output), it was hypothesized that intention component of the treatment would enhance re-acquisition of picture naming more than the attention component. Patients with moderate and severe word-finding impairment showed gains with both treatments but greater incremental improvement from one treatment phase to the next with the intention than the attention treatment. Thus, the hypothesis that intention component would be a more active constituent than the attention component was confirmed for these patients. Patients with profound word-finding impairment showed some improvement with both treatments but no differential effects for the intention treatment. Almost all patients who showed treatment gains on either treatment also demonstrated generalization from trained to untrained items. (JINS, 2007, 13, 582–594.)

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Corresponding author

Correspondence and reprint requests to: Bruce Crosson, Ph.D., Brain Rehabilitation Research Center (151A), Malcom Randall VA Medical Center, 1601 SW Archer Road, Gainesville, Florida 32608-1197. E-mail: bcrosson@phhp.ufl.edu

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