Skip to main content Accessibility help
×
Home

A review of the impact of exercise on treatment-related fatigue among patients receiving adjuvant radiotherapy for breast cancer

  • Fiona McNally (a1), Paul H. Shepherd (a2) and Terri Flood (a2)

Abstract

Purpose

To evaluate the use of exercise in managing fatigue in breast cancer patients undergoing adjuvant radiotherapy. To explore the effectiveness of different exercise practices and explore how optimum management of fatigue might be achieved.

Method

A CINAHL (Cumulative Index to Nursing and Allied Health Literature) database search of literature was undertaken and publications screened for retrieval with 24 qualifying for inclusion in the review.

Results

There is evidence to support various forms of exercise including aerobic, resistance, alternative and combination exercise in the management of fatigue in early stage breast cancer patients undergoing adjuvant radiotherapy. The benefits of exercise for patients with later stage and metastatic disease is less clear and there is a lack of published research related to this category of patient.

Conclusion

Exercise is considered a safe, non-pharmacological intervention for early stage breast cancer patients receiving adjuvant radiotherapy. Further investigation is required into optimum exercise interventions and the effectiveness and viability of supervised and unsupervised models. Patient centred tailored advice and guidance needs to be developed and effectively promoted by therapeutic radiographers in order for patients to fully realise the benefit.

Copyright

Corresponding author

Author for correspondence: Paul H Shepherd, School of Health Sciences, Ulster University, Newtownabbey, County Down, BT37 0QB, Northern Ireland, UK. Tel: +44 (0) 28 9036 6233. E-mail: PH.Shepherd@ulster.ac.uk

Footnotes

Hide All

Cite this article: McNally F, Shepherd PH, Flood T. (2019) A review of the impact of exercise on treatment-related fatigue among patients receiving adjuvant radiotherapy for breast cancer. Journal of Radiotherapy in Practice18: 295–300. doi: 10.1017/S1460396918000754

Footnotes

References

Hide All
1. Cancer Research UK. Breast Cancer Statistics. 2015. http://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/breast-cancer. Accessed on 21st October 2018.
2. Lipsett, A, Barrett, S, Haruna, F, Mustain, K, O’Donovan, A. The impact of exercise during adjuvant radiotherapy for breast cancer on fatigue and quality of life: a systematic review and meta-analysis. Breast 2017; 32: 144155.10.1016/j.breast.2017.02.002
3. Van Vulpen, J K, Peeters, P H M, Velthuis, M J, Van der Wall, E, May, A M. Effects of physical exercise during adjuvant breast cancer treatment on physical and psychosocial dimensions of cancer-related fatigue: a meta-analysis. Maturitas 2016; 85: 104111.10.1016/j.maturitas.2015.12.007
4. Berger, A M, Gerber, L, Mayer, D K. Cancer related fatigue—implications for breast cancer survivors. Cancer 2012; 118 (58): 22612269.
5. Mustain, K, Peppone, L, Darling, T V, Palesh, O, Heckler, C E, Morrow, G R. A 4-week home based aerobic and resistance exercise programme during radiation therapy: a pilot randomized clinical trial. J Support Oncol 2009; 7: 158167.
6. Alcantara-Silva, T R, Freitas-Junior, R, Freitas, N, Machado, G. Fatigue related to radiotherapy for breast and/or gynaecological cancer. J Clin Nurs 2013; 22: 26792686.10.1111/jocn.12236
7. Mock, V, Frangakis, C, Davidson, N E et al. Exercise manages fatigue during breast cancer treatment: a randomised control trial. Psycho-oncology 2005; 14: 464477.10.1002/pon.863
8. Harte, J. Exercise during and after breast cancer treatment. Altern Compliment Ther 2014; 20: 259262.10.1089/act.2014.20503
9. Hsieh, C, Sprod, L, Hydock, D, Carter, S, Hayward, D, Schneider, C M. Effects of a supervised exercise intervention on recovery from treatment regimens in breast cancer survivors. Oncol Nurs Forum 2008; 35: 909915.10.1188/08.ONF.909-915
10. Campbell, A, Mutrie, N, White, F, McGuire, F, Kearney, N. A pilot study of a supervised exercise programme as a rehabilitation treatment for women with breast cancer receiving adjuvant treatment. Eur J Oncol Nurs 2005; 9: 5663.10.1016/j.ejon.2004.03.007
11. Furmaniak, A C, Menig, M, Markes, M H. Exercise for women receiving adjuvant therapy for breast cancer (review). Cochrane Database Syst Rev 2016; 9.10.1002/14651858.CD005001.pub3
12. Ligibel, J A, Partridge, A, Giobbie-Hurder, A et al. Physical and psychological outcomes among women in a telephone-based exercise intervention during adjuvant therapy for early stage breast cancer. J Women’s Health 2010; 19: 15531559.10.1089/jwh.2009.1760
13. Steindorf, K, Schmidt, M E, Klassen, O et al. Randomized controlled trial of resistance training in breast cancer patients receiving adjuvant therapy: results on cancer-related fatigue and quality of life. Ann of Oncol 2014; 25: 22372243.10.1093/annonc/mdu374
14. Schmidt, M E, Wiskemann, J, Armbrust, P, Schneeweiss, A, Ulrich, C, Steindorf, K. Effects of resistance exercise on fatigue and quality of life in breast cancer patients undergoing adjuvant chemotherapy: a randomized control trial. Cancer Ther 2015; 137: 471480.
15. Chandwani, K D, Perkins, G, Nagendra, H R et al. Randomized, controlled trial of yoga in women with breast cancer undergoing radiotherapy. Clin Oncol 2014; 32: 10581065.10.1200/JCO.2012.48.2752
16. Lotzke, D, Wiedemann, F, Recchia, D et al. Iyengar-Yoga compared to exercise as a therapeutic intervention during (neo) adjuvant therapy in women with stage I-III breast cancer. Evid Based Complementary Altern Med 2016; 2016: 18.10.1155/2016/5931816
17. Reis, D, Walsh, E, Young-McCaughan, S, Jones, T. Effects of Nia exercise in women receiving radiation therapy for breast cancer. Oncol Nurs Forum 2013; 40: 374382.10.1188/13.ONF.E374-E381
18. Chen, Z, Meng, Z, Milbury, K et al. Qigong improves the quality of life in women undergoing radiotherapy for breast cancer. Am Cancer Soc 2013; 119: 16901698.
19. Meneses-Echavez, J F, Gonzalez-Jimenez, E, Ramirez-Velez, R. Supervised exercise reduces cancer-related fatigue: a systematic review. J Physiother 2015; 61: 39.10.1016/j.jphys.2014.08.019
20. Windor, P M, Potter, J, McAdam, K, McCowan, C. Evaluation of a fatigue initiative: information on exercise for patients receiving cancer treatment. Clin Oncol 2009; 21: 473482.10.1016/j.clon.2009.01.009
21. Carayol, M, Bernard, P, Boiche, J et al. Psycological effect of exercise in women with breast cancer receiving adjuvant therapy: what is optimal dose needed. Ann of Oncol 2013; 24: 291300.10.1093/annonc/mds342
22. Carayol, M, Delpierre, C, Bernard, P, Ninot, G. Population-, intervention- and methodology-related characteristics of clinical trials impact exercise efficacy during adjuvant therapy for breast cancer: a meta-regression analysis. Psycooncology 2015; 24: 737747.10.1002/pon.3727
23. Romero, S, Li, Q, Mao, J J. Factors and barriers associated with changes in physical activity after cancer diagnosis. J Clin Oncol 2017; 35 (5): 162.10.1200/JCO.2017.35.5_suppl.162
24. Schmitz, K, DiSipio, T, Gordon, L, Hayes, S. Adverse breast cancer treatment effects: the economic case for making rehabilitative programmes standard of care. Support Care Cancer 2015; 23: 18071817.10.1007/s00520-014-2539-y
25. Groeneveld, I F, De Boer, A G, Frings-Dresen, M H. Physical exercise and return to work. J Cancer Surviv 2013; 7: 237246.10.1007/s11764-012-0264-4
26. Abed, J, Dolan, L, Jones, J, Dinniwell, R. Impact of exercise on reported fatigue and anxiety levels in early stage breast cancer undergoing radiotherapy. J Med Imaging Radiat Sci 2017; 48: S5.10.1016/j.jmir.2017.02.015

Keywords

A review of the impact of exercise on treatment-related fatigue among patients receiving adjuvant radiotherapy for breast cancer

  • Fiona McNally (a1), Paul H. Shepherd (a2) and Terri Flood (a2)

Metrics

Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed