The basal part of the Upper Cretaceous, mid-Campanian to Maastrichtian Izumi Group of the Izumi Mountains and Awaji Island, Southwest Japan, contains the most diverse gastropod fauna of this age in Japan. This paper discriminates 19 species and describes two new genera: Atira tricarinata n. sp., Ataphrus (s.s.) sp. A, Ataphrus (s.s.) sp. B, Globularia (s.s.) izumiensis n. sp., Lysis izumiensis n. sp., Trichotropis? sp., Deussenia takinoikensis n. sp., Volutilithes antiqua n. sp., Pseudoperissitys bicarinata Nagao and Otatume, Nekewis sp., Nipponitys inouei n. gen. and sp., Nipponitys acutangularis n. gen. and sp., Nipponitys sp. cf. N. magna (Kalishevitsch), Calorebama cretacea n. sp., Taniella japonica n. gen. and sp., Amuletum (s.s.) sp., Biplica osakensis n. sp., Biplica sphaerica n. sp., and Cylichna sp. The family Ampullospiridae is assigned to the suborder Architaenioglossa from the superfamily Naticacea. The enigmatic genus Lysis is tentatively assigned to the Calyptraeidae. Taniella japonica n. sp. is the oldest member of the family Olividae, and Calorebama cretacea n. sp. is the oldest member of the subfamily Pseudolivinae. Occurrence of Atira, Ataphrus, Biplica, and five perissityids further supports close communication of the northwestern Pacific Late Cretaceous gastropod faunas with those of the North American Pacific coastal areas.