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A Case of Childhood Pellagra with Psychosis

  • L. A. Hersov (a1)

Extract

Pellagra is a rare disease in Great Britain. The majority of cases occur among patients in mental hospitals and institutions (Stannus and Gibbons, 1934), and more recently it has been described as an accompaniment or complication of a chronic psychosis (Hardwick, 1946). Sporadic cases do arise in the general population (Davis and Hinden, 1941), but it is likely that in many instances the disease goes unrecognized (Deeny, 1942). Pellagra is particularly uncommon in British children (Greenfield and Holmes, 1939), although observers in areas where the disease is rife are of the opinion that it is found more frequently in children than in adults (Weston and Weston, 1948).

Mental symptoms are frequent in pellagra and may, in fact, precede the other manifestations (Sydenstricker, 1943). Severe psychoses occur in untreated cases and depressive, manic and paranoid reactions have been described (Hardwick, 1946). In children, however, symptoms are usually mild and mania or delirium is not often present (Holt and Mcintosh, 1953); therefore this case of pellagra with a psychotic reaction in a 10-year-old English schoolboy may be of interest.

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References

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Bicknell, F., and Prescott, F., The Vitamins in Medicine, 1953. 3rd ed., p. 352. London: William Heinemann.
Chick, H., Nutr. Abst. and Revs., 1951, 20, 523.
Davis, E., and Hinden, E., Lancet, 1941, i, 10.
Deeny, J., Brit. Med. J., 1942, i, 157.
Dodd, K., in Seale Harris's Clinical Pellagra, 1941, p. 341. St. Louis: C. V. Mosby & Co.
Ford, F. R., Diseases of the Nervous System in Infancy and Childhood, 1952. 3rd ed., p. 768. Oxford: Blackwell Scientific Publications.
Frostig, J. P., and Spies, T. D., Amer. J. Med. Sci., 1940, 199, 268.
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Greenfield, J. G., and MacD Holmes, J., Brit. Med. J., 1939, i, 815.
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Kanner, L., Child Psychiatry, 1948. 2nd ed., p. 449. Oxford: Blackwell Scientific Publications.
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Weston, W., and Weston, W. Jr., in Brenneman's Practice of Paediatrics, 1948. Vol. 1, Ch. 34, p. 1. Hagerstown: W. F. Prior & Co
Yudkin, J., Lectures on the Scientific Basis of Medicine, 1951–2. Vol. 1, p. 364. University of London: The Athlone Press.

A Case of Childhood Pellagra with Psychosis

  • L. A. Hersov (a1)

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A Case of Childhood Pellagra with Psychosis

  • L. A. Hersov (a1)
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