Chalcogenide glasses of the systems Ge–Sn–Se, Ge–Se–Te, and Ge–Sn–Se–Te have been prepared. Several compositions were found suitable for drawing fibers for CO2 laser radiation (λ = 10.6 μm) transmission. The glasses were characterized by x-ray diffraction, DSC (Differential Scanning Calorimetry), SEM with EDX analysis, FTIR spectrometry, density, and microhardness measurements. The glass transition temperature and microhardness of Ge–Se–Sn and Ge–Sn–Se–Te glasses decreased with increasing Sn content, for most of the samples. The region of high IR transparency of Ge–Se–Sn, Ge–Se–Te, and Ge–Sn–Se–Te glasses was slightly expanded (1–2 μm) toward longer wavelengths, compared to Ge–Se glasses, mainly for the glasses containing 70 at.% Se. The intensity of the impurity absorption peak of Ge–O (at λ ∼ 12.8 μm), which usually appears in Ge–Se glasses, was reduced or absent in Ge–Sn–Se–Te glasses. The best fibers were produced with the glass composition Ge–0.8Sn0.2Se3.5Te0.5. An attenuation of 20 dB/m at 10.6 μm, and a transmitted maximum power density of 2.4 ⊠ 106 W/m2 were measured. The mechanical and optical characteristics of these glasses have been related to the glasses structure. Corresponding to the reduced masses of the bonds formed in the Ge–Sn–Se–Te system (in the amorphous region), it is expected that the multiphonon edge is slightly shifted. As a consequence, as was measured, the transparency region has been expanded by less than 2 μm toward longer wavelengths.