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Synthesis and characterization of pH and temperature double-sensitive nanocomposite hydrogels consisting of poly(dimethylaminoethyl methacrylate) and clay

Published online by Cambridge University Press:  23 April 2013

Yi Chen ,
Weijian Xu ,
Yuanqin Xiong ,
Chang Peng ,
Wenyong Liu ,
Guangsheng Zeng  and
Yue Peng
Yi Chen
Affiliation:
Department of Applied Chemistry, Institute of Polymer Research, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China; and Department of Polymer Materials and Engineering, Key Laboratory of Advanced Materials and Technology for Packaging of Hunan University of Technology, Zhuzhou 412008, China
Weijian Xu*
Affiliation:
Department of Applied Chemistry, Institute of Polymer Research, College of Chemistry and Chemical Engineering, Hunan University; Changsha 410082, China
Yuanqin Xiong
Affiliation:
Department of Applied Chemistry, Institute of Polymer Research, College of Chemistry and Chemical Engineering, Hunan University; Changsha 410082, China
Chang Peng
Affiliation:
Department of Applied Chemistry, Institute of Polymer Research, College of Chemistry and Chemical Engineering, Hunan University; Changsha 410082, China
Wenyong Liu
Affiliation:
Department of Polymer Materials and Engineering, Key Laboratory of Advanced Materials and Technology for Packaging of Hunan University of Technology, Zhuzhou 412008, China
Guangsheng Zeng
Affiliation:
Department of Polymer Materials and Engineering, Key Laboratory of Advanced Materials and Technology for Packaging of Hunan University of Technology, Zhuzhou 412008, China
Yue Peng
Affiliation:
Department of Polymer Materials and Engineering, Key Laboratory of Advanced Materials and Technology for Packaging of Hunan University of Technology, Zhuzhou 412008, China
*
a)Address all correspondence to this author. e-mail: weijxu@hnu.net.cn
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Abstract

The monomer dimethylaminoethyl methacrylate (DMAEMA) was cross-linked by clay Laponite XLG and Laponite XLS, respectively, in situ free-radical polymerization to prepare nanocomposite gels (named as G-NC gels and S-NC gels). From the analysis of yield, transparency, Fourier transform infrared spectroscopy, x-ray, and scanning electron microscopy, it was proved that the clay Laponite XLS is an appropriate cross-linker for preparing PDMAEMA NC gels with better homogeneous and higher yield due to the uniform dispersion of clay in gels. The resulting S-NC gels show obvious temperature and pH double sensitiveness, and the lowest critical solution temperatures of gels with a low clay content are close to the temperature of the human body, which makes this gel a potential candidate for application in drug release. Comparing with the gels cross-linked by a chemical cross-link agent, the S-NC gels exhibit a considerable improvement in the mechanical properties, swelling ratio, and deswelling rate. The properties of S-NC gels could be adjusted by controlling the content of clay.

Type
Articles
Information
Journal of Materials Research , Volume 28 , Issue 10 , 28 May 2013 , pp. 1394 - 1404
Copyright
Copyright © Materials Research Society 2013 

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