Skip to main content Accessibility help
×
Home

High-speed photography of the development of microdamage in trabecular bone during compression

  • Philipp J. Thurner (a1), Blake Erickson (a1), Zachary Schriock (a1), John Langan (a2), Jeff Scott (a2), Maria Zhao (a2), James C. Weaver (a3), Georg E. Fantner (a4), Patricia Turner (a4), Johannes H. Kindt (a4), Georg Schitter (a4), Daniel E. Morse (a3) and Paul K. Hansma (a4)...

Abstract

The mechanical properties of healthy and diseased bone tissue were extensively studied in mechanical tests. Most of this research was motivated by the immense costs of health care and social impacts due to osteoporosis in post-menopausal women and the aged. Osteoporosis results in bone loss and change of trabecular architecture, causing a decrease in bone strength. To address the problem of assessing local failure behavior of bone, we combined mechanical compression testing of trabecular bone samples with high-speed photography. In this exploratory study, we investigated healthy, osteoarthritic, and osteoporotic human vertebral trabecular bone compressed at high strain rates. Apparent strains were found to transfer into to a broad range of local strains. Strained trabeculae were seen to whiten with increasing strain. Comparison of whitened regions seen in high-speed photography sequences with scanning electron micrographs showed that the observed whitening was due to the formation of microcracks. From the results of a motion energy filter applied to the recorded movies, we saw that the whitened areas are, presumably, also areas of high deformation. In summary, high-speed photography allows the detection of microdamage in real time, leading toward a better understanding of the local processes involved in bone failure.

Copyright

Corresponding author

a) Address all correspondence to this author. e-mail: thurner@physics.ucsb.edu This paper was selected as the Outstanding Meeting Paper for the 2005 MRS Spring Meeting Symposium L Proceedings, Vol. 874.

References

Hide All
1.Keaveny, T.M., Hayes, W.C.: A 20-year perspective on the mechanical properties of trabecular bone. J. Biomech. Eng. 115, 534 (1993).
2.III, L.J. Melton, Chrischilles, E.A., Cooper, C., Lane, A.W., Riggs, B.L.: Perspective. How many women have osteoporosis? J. Bone Miner. Res. 7, 1005 (1992).
3.Kanis, J.A.: Osteoporosis: A view into the next century. Neth. J. Med. 50(5), 198 (1997).
4.McBroom, R.J., Hayes, W.C., Edwards, W.T., Goldberg, R.P., III, A.A. White: Prediction of vertebral body compressive fracture using quantitative computed tomography. J. Bone Joint Surg. Am. 67, 1206 (1985).
5.Silva, M.J., Keaveny, T.M., Hayes, W.C.: Load sharing between the shell and centrum in the lumbar vertebral body. Spine 22(2)), 140 (1997).
6.Muller, R., Gerber, S.C., Hayes, W.C.: Micro-compression: A novel technique for the nondestructive assessment of local bone failure. Technol. Health Care 6, 433 (1998).
7.Bay, B.K., Smith, T.S., Fyhrie, D.P., Saad, M.: Digital volume correlation: Three-dimensional strain mapping using x-ray tomography. Exp. Mech. 39(3), 217 (1999).
8.Nicolella, D.P., Nicholls, A.E., Lankford, J., Davy, D.T.: Machine vision photogrammetry: A technique for measurement of microstructural strain in cortical bone. J. Biomech. 34(1), 135 (2001).
9.Nazarian, A., Muller, R.: Time-lapsed microstructural imaging of bone failure behavior. J. Biomech. 37(1), 55 (2004).
10.Thurner, P., Wyss, P., Voide, R., Stauber, M., Muller, B., Stampanoni, M., Hubell, J.A., Muller, R., Sennhauser, U. Functional micro-imaging of soft and hard tissue using synchrotron light, in Developments in X-Ray Tomography IV, edited by Bonse, U. (The International Society for Optical Engineering [SPIE], Bellingham, WA), Vol. 5535, pp. 112.
11.Thurner, P.J., Wyss, P., Voide, R., Stauber, M., Stampanoni, M., Sennhauser, U., Muller, R. Time-lapsed investigation of three-dimensional failure and damage accumulation in trabecular bone using snychrotron light. Bone (2006, in press).
12.Currey, J.D.: Bones: Structure and Mechanics (Princeton University Press, Princeton, NJ, 2002).
13.Bay, B.K.: Texture correlation: a method for the measurement of detailed strain distributions within trabecular bone. J. Orthop. Res. 13(2), 258 (1995).
14.Adelson, E.H., Bergen, J.R.: Spatiotemporal energy models for the perception of motion. J. Opt. Soc. Am. A, Opt. Image Sci. Vis. 2(2), 284 (1985).
15.Odgaard, A., Hvid, I., Linde, F.: Compressive axial strain distributions in cancellous bone specimens. J. Biomech. 22, 829 (1989).
16.Bonfield, W., Grynpas, M.D.: Spiral fracture of cortical bone. J. Biomech. 15, 555 (1982).
17.Osvalder, A.L., Neumann, P., Lovsund, P., Nordwall, A.: A method for studying the biomechanical load response of the (in-vitro) lumbar spine under dynamic flexion shear loads. J. Biomech. 26, 1227 (1993).
18.Cherry, B.W., Hin, T.S.: Stress whitening in polyethylene. Polymer 22, 1610 (1981).
19.Nalla, R.K., Kinney, J.H., Ritchie, R.O.: Mechanistic fracture criteria for the failure of human cortical bone. Nat. Mater. 2(3), 164 (2003).
20.Fantner, G.E., Hassenkam, T., Kindt, J.H., Weaver, J.C., Birkedal, H., Pechenik, L., Cutroni, J.A., Cidade, G.A.G., Stucky, G.D., Morse, D.E., and Hansma, P.K.: Sacrificial bonds and hidden length dissipate energy as mineralized fibrils separate during bone fracture. Nature Mater. 4 612 (2005).
21.Nagaraja, S., Couse, T.L., Guldberg, R.E.: Trabecular bone microdamage and microstructural stresses under uniaxial compression. J. Biomech. 38, 707 (2005).

Keywords

Related content

Powered by UNSILO

High-speed photography of the development of microdamage in trabecular bone during compression

  • Philipp J. Thurner (a1), Blake Erickson (a1), Zachary Schriock (a1), John Langan (a2), Jeff Scott (a2), Maria Zhao (a2), James C. Weaver (a3), Georg E. Fantner (a4), Patricia Turner (a4), Johannes H. Kindt (a4), Georg Schitter (a4), Daniel E. Morse (a3) and Paul K. Hansma (a4)...

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed.