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Effect of nanohydroxyapatite, antibiotic, and mucosal defensive agent on the mechanical and thermal properties of glass ionomer cements for special needs patients

Published online by Cambridge University Press:  04 March 2018

Manila Chieruzzi Open the ORCID record for Manila Chieruzzi [Opens in a new window] ,
Stefano Pagano ,
Guido Lombardo ,
Lorella Marinucci ,
José M. Kenny ,
Luigi Torre  and
Stefano Cianetti
Manila Chieruzzi
Affiliation:
Civil and Environmental Engineering Department, UdR INSTM, University of Perugia, Terni 05100, Italy
Stefano Pagano*
Affiliation:
Department of Biomedical and Surgical Sciences, School of Medicine, Odontostomatological University Centre: Chair Prof. Stefano Cianetti, University of Perugia, Perugia 06156, Italy
Guido Lombardo
Affiliation:
Department of Biomedical and Surgical Sciences, School of Medicine, Odontostomatological University Centre: Chair Prof. Stefano Cianetti, University of Perugia, Perugia 06156, Italy
Lorella Marinucci
Affiliation:
Department of Experimental Medicine Section of Biosciences and Medical Embriology, University of Perugia, Perugia 06156, Italy
José M. Kenny
Affiliation:
Civil and Environmental Engineering Department, UdR INSTM, University of Perugia, Terni 05100, Italy
Luigi Torre
Affiliation:
Civil and Environmental Engineering Department, UdR INSTM, University of Perugia, Terni 05100, Italy
Stefano Cianetti
Affiliation:
Department of Biomedical and Surgical Sciences, School of Medicine, Odontostomatological University Centre: Chair Prof. Stefano Cianetti, University of Perugia, Perugia 06156, Italy
*
a)Address all correspondence to this author. e-mail: stefano.pagano@unipg.it
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Abstract

Special needs patients often require specific dental treatments and modified restorative materials that reduce clinical discomfort. Starting from glass ionomer cements (GICs), some different fillers were added to improve their mechanical and clinical performances. The effect of nanohydroxyapatite, antibiotic, and mucosal defensive agent on the mechanical and thermal properties of GICs was investigated. Compressive tests, calorimetric analysis, and morphological investigation were conducted. The middle percentages of fillers increased the elastic modulus while the highest decreases are recorded for highest percentages. Filler and environment also influence the compressive strengths and toughness. The introduction of fillers led to a reduction of the enthalpy with a maximum decrease with the middle percentage. The morphological characterization showed a good dispersion of the fillers. The filler percentages should be selected with a compromise between the elastic modulus, the compressive strength, and the curing time. Obtaining new materials with good clinical and mechanical properties can represent an innovative aspect of this work with positive implication in clinical practice, mainly in uncollaborative patients in which the use of traditional protocols is problematic.

Keywords

calorimetryadditiveselastic properties
Type
Articles
Information
Journal of Materials Research , Volume 33 , Issue 6 , 28 March 2018 , pp. 638 - 649
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Copyright
Copyright © Materials Research Society 2018 

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Footnotes

Contributing Editor: Jinju Chen

References

REFERENCES

Deepalakshmi, M., Poorni, S., Migliani, R., Rajamani, R., and Ramachandran, S.: Evaluation of the antibacterial and physical properties of glass ionomer cements containing chlorhexidine and cetrimide: An in vitro study. Indian J. Dent. Res. 21, 552 (2010).Google Scholar
Frencken, J. and van Amerongen, W.: The Atraumatic Restorative Treatment Approach, Dental Caries: The Disease and its Clinical Management (Blackwell Munksgaard, Oxford, 2008); p. 427.Google Scholar
Chieruzzi, M., Pagano, S., Moretti, S., Pinna, R., Milia, E., Torre, L., and Eramo, S.: Nanomaterials for tissue engineering in dentistry. Nanomaterials 6, 134 (2016).Google Scholar
Lucas, M.E., Arita, K., and Nishino, M.: Toughness, bonding and fluoride-release properties of hydroxyapatite-added glass ionomer cement. Biomaterials 24, 3787 (2003).Google Scholar
Weng, Y., Guo, X., Chong, V., Howard, L., Gregory, R., and Xie, D.: Synthesis and evaluation of a novel antibacterial dental resin composite with quaternary ammonium salts. J. Biomed. Sci. Eng. 4, 147 (2011).Google Scholar
Deligeorgi, V., Wilson, N.H.F., and Mjor, I.A.: An overview of reasons for the placement and replacement of restorations. J. Dent. Res. 77, 714 (1998).Google Scholar
Marti, L., Lata, M., Ferraz-Santos, B., Azevedo, E., Giro, E., and Zuanon, A.: Addition of chlorhexidine gluconate to a glass ionomer cement as study on mechanical, physcial and antibacterial properties. Braz. Dent. J. 25, 33 (2014).Google Scholar
de Castilho, A.R.F., Duque, C., Negrini, T.D., Sacono, N.T., de Paula, A.B., Costa, C.A.D., Spolidorio, D.M.P., and Puppin-Rontani, R.M.: In vitro and in vivo investigation of the biological and mechanical behaviour of resin-modified glass-ionomer cement containing chlorhexidine. J. Dent. 41, 155 (2013).Google Scholar
Chieruzzi, M., Pagano, S., De Carolis, C., Eramo, S., and Kenny, J.M.: Scanning electron microscopy evaluation of dental root resorption associated with granuloma. Microsc. Microanal. 21, 1264 (2015).CrossRefGoogle ScholarPubMed
Mittal, S., Soni, H., Sharma, D., Mittal, K., Pathania, V., and Sharma, S.: Comparative evaluation of the antibacterial and physical properties of conventional glass ionomer cement containing chlorhexidine and antibiotics. J. Int. Soc. Prev. Community Dent. 5, 268 (2015).Google Scholar
Goenka, S., Balu, R., and Kumar, T.S.S.: Effects of nanocrystalline calcium deficient hydroxyapatite incorporation in glass ionomer cements. J. Mech. Behav. Biomed. Mater. 7, 69 (2012).Google Scholar
Gu, Y.W., Yap, A.U.J., Cheang, P., and Khor, K.A.: Effects of incorporation of HA/ZrO2 into glass ionomer cement (GIC). Biomaterials 26, 713 (2005).Google Scholar
Garcia-Contreras, R., Scougall-Vilchis, R.J., Contreras-Bulnes, R., Sakagami, H., Morales-Luckie, R.A., and Nakajima, H.: Mechanical, antibacterial and bond strength properties of nano-titanium-enriched glass ionomer cement. J. Appl. Oral Sci. 23, 321 (2015).Google Scholar
Nicholson, J.W., Hawkins, S.J., and Smith, J.E.: The incorporation of hydroxyapatite into glass-polyalkenoate (glass-ionomer) cements—A preliminary-study. J. Mater. Sci.: Mater. Med. 4, 418 (1993).Google Scholar
Yap, A.U.J., Pek, Y.S., Kumar, R.A., Cheang, P., and Khor, K.A.: Experimental studies on a new bioactive material: HA ionomer cements. Biomaterials 23, 955 (2002).Google Scholar
Arita, K., Lucas, M.E., and Nishino, M.: The effect of adding hydroxyapatite on the flexural strength of glass ionomer cement. Dent. Mater. J. 22, 126 (2003).Google Scholar
Chae, M.H., Lee, Y.K., Kim, K.N., Lee, J.H., Choi, B.J., Choi, H.J., and Park, K.T.: The effect of hydroxyapatite on bonding strength in light curing glass ionomer dental cement Key Engin. Mater. 309–311, 881–884 (2006).Google Scholar
Moshaverinia, A., Ansari, S., Moshaverinia, M., Roohpour, N., Darr, J.A., and Rehman, I.U.: Effects of incorporation of hydroxyapatite and fluoroapatite nanobioceramics into conventional glass ionomer cements (GIC). Acta Biomater. 4, 432 (2008).Google Scholar
Moshaverinia, A., Ansari, S., Movasaghi, Z., Billington, R.W., Darr, J.A., and Rehman, I.U.: Modification of conventional glass-ionomer cements with N-vinylpyrrolidone containing polyacids, nano-hydroxy and fluoroapatite to improve mechanical properties. Dent. Mater. 24, 1381 (2008).Google Scholar
Mu, Y., Zang, G., Sun, H., and Wang, C.: Effect of nano-hydroxyapatite to glass ionomer cement. Hua xi kou qiang yi xue za zhi 25, 544 (2007).Google Scholar
Takahashi, Y., Imazato, S., Kaneshiro, A.V., Ebisu, S., Frencken, J.E., and Tay, F.R.: Antibacterial effects and physical properties of glass-ionomer cements containing chlorhexidine for the ART approach. Dent. Mater. 22, 647 (2006).Google Scholar
Sanders, B.J., Gregory, R.L., Moore, K., and Avery, D.R.: Antibacterial and physical properties of resin modified glass-ionomers combined with chlorhexidine. J. Oral Rehabil. 29, 553 (2002).Google Scholar
Yesilyurt, C., Er, K., Tasdemir, T., Buruk, K., and Celik, D.: Antibacterial activity and physical properties of glass-ionomer cements containing antibiotics. Oper. Dent. 34, 18 (2009).Google Scholar
Pinheiro, S.L., Simionato, M.R.L., Imparato, J.C.P., and Oda, M.: Antibacterial activity of glass-ionomer cement containing antibiotics on caries lesion microorganisms. Am. J. Dent. 18, 261 (2005).Google Scholar
Ferreira, J., Pinheiro, S., Sampaio, F., and Menezes, V.: Use of glass ionomer cement containing antibiotics to seal off infected dentin: A randomized clinical trial. Braz. Dent. J. 24, 68 (2013).CrossRefGoogle ScholarPubMed
Katayama, S., Nishizawa, K., Hirano, M., Yamamura, S., and Momose, Y.: Effect of polaprezinc on heating of acetic acid-induced stomatitis in hamsters. J. Pharm. Pharmaceut. Sci. 3, 113 (2000).Google Scholar
Farrugia, C. and Camilleri, J.: Antimicrobial properties of conventional restorative filling materials and advances in antimicrobial properties of composite resins and glass ionomer cements—A literature review. Dent. Mater. 31, E89 (2015).Google Scholar
Botelho, M.G.: Inhibitory effects on selected oral bacteria of antibacterial agents incorporated in a glass ionomer cement. Caries Res. 37, 108 (2003).Google Scholar
Mueller, H.J., Bapna, M.S., and Fan, P.L.: Heats of reactions between dentin bonding agents and tooth components. J. Oral Rehabil. 21, 699 (1994).Google Scholar
Bjorndal, L. and Larsen, T.: Changes in the cultivable flora in deep carious lesions following a stepwise excavation procedure. Caries Res. 34, 502 (2000).CrossRefGoogle ScholarPubMed
Duque, C., Negrini, T.D., Sacono, N.T., Spolidorio, D.M.P., Costa, C.A.D., and Hebling, J.: Clinical and microbiological performance of resin-modified glass-ionomer liners after incomplete dentine caries removal. Clin. Oral Invest. 13, 465 (2009).Google Scholar
Pinto, A.S., de Araujo, F.B., Franzon, R., Figueiredo, M.C., Henz, S., Garcia-Godoy, F., and Maltz, M.: Clinical and microbiological effect of calcium hydroxide protection in indirect pulp capping in primary teeth. Am. J. Dent. 19, 382 (2006).Google Scholar
Poggio, C., Arciola, C.R., Cepurnykh, S., Chiesa, M., Scribante, A., Selan, L., Imbriani, M., and Visai, L.: In vitro antibacterial activity of different self-etch adhesives. Int. J. Artif. Organs 35, 487 (2012).Google Scholar
Imazato, S., Kuramoto, A., Takahashi, Y., Ebisu, S., and Peters, M.C.: In vitro antibacterial effects of the dentin primer of Clearfil Protect Bond. Dent. Mater. 22, 527 (2006).Google Scholar
Beyth, N., Yudovin-Farber, I., Bahir, R., Domb, A.J., and Weissa, E.: Antibacterial activity of dental composites containing quaternary ammonium polyethylenimine nanoparticles against streptococcus mutans. Biomaterials 27, 3995 (2006).Google Scholar
Melo, M.A.S., Guedes, S.F.F., Xu, H.H.K., and Rodrigues, L.K.A.: Nanotechnology-based restorative materials for dental caries management. Trends Biotechnol. 31, 459 (2013).Google Scholar
Choudhary, K. and Nandhal, B.: Comparative evaluation of shear bond strength of nano-hydroxyapatite incorporated glass ionomer cement and conventional glass ionomer cement on dense synthetic hydroxyapatite disk: An in vitro study. Indian J. Dent. Res. 26, 170 (2015).Google Scholar