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Exploration of interactions of ‘blood-nano interface’ of carbon-based nanomaterials for biomedical applications

Published online by Cambridge University Press:  31 May 2019

Vishal Singh
Department of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, Uttar Pradesh 211012, India
Aparajita Basu
Department of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, Uttar Pradesh 211012, India
P.M. Shivapriya
Department of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, Uttar Pradesh 211012, India
Pritish Kumar Varadwaj
Department of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, Uttar Pradesh 211012, India
Sintu Kumar Samanta
Department of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, Uttar Pradesh 211012, India
Amaresh Kumar Sahoo
Department of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, Uttar Pradesh 211012, India
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One of the most promising nanoscale materials which fascinated researchers for the last few decades owing to its unique optoelectronics and physicochemical properties are carbon-based nanomaterials (CBNs). Various forms of CBNs have been developed such as single and multi-walled carbon nanotubes, graphene, fullerenes, nanodiamonds, and fluorescent carbon quantum dots (C-Dots) whereas each form is having its own exceptional properties owing to its dimensionalities and architectures. The advent of these unique classes of nanoscale materials opens up a spectrum of new opportunities and possibilities in employing these in emerging areas of biomedical. However, successful biomedical applications greatly rely on the likelihood of the comprehensive understanding of physicochemical interactions and biological responses of CBNs. Herein, we have tried to explore the ‘blood-CBNs’ interface by including the findings of recent studies. The role of surface modifications and functionalization in order to mitigate the adverse outcomes has also been incorporated.

Copyright © Materials Research Society 2019 

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These authors contributed equally to this work.

This section of Journal of Materials Research is reserved for papers that are reviews of literature in a given area.


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