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Vestibular test findings in individuals with auditory neuropathy: review

  • S K Sinha (a1), A Barman (a1), N K Singh (a1), G Rajeshwari (a2) and R Sharanya (a1)...



The vestibulocochlear nerve is a sensory nerve that serves the organs of hearing and equilibrium. Neuropathies of the nerve, particularly auditory neuropathy, may be caused by primary demyelination or axonal disease. Cochlear amplification function is normal in cases of auditory neuropathy, but afferent neural conduction in the auditory pathway is disordered. It is highly probable that the vestibular nerve has some involvement in disorders affecting the cochlear nerve.


To provide an overview of vestibular test findings in individuals with auditory neuropathy.


A structured literature search was carried out, with no restrictions to the dates searched.


Auditory neuropathy implicated the vestibular branch of the VIIIth cranial nerve as well as the cochlear nerve. However, there was variability in terms of vestibular test findings.


Corresponding author

Address for correspondence: Dr S K Sinha, Department of Audiology, All India Institute of Speech and Hearing, Mysore, Karnataka, India - 570006 Fax: +91 821 2510515 E-mail:


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1Starr, A, Picton, TW, Sininger, Y, Hood, LJ, Berlin, CI. Auditory neuropathy. Brain 1996;119:741–53
2Akdogan, O, Selcuk, A, Ozcan, I, Dere, H. Vestibular nerve functions in children with auditory neuropathy. Int J Pediatr Otorhinolaryngol 2008;72:415–19
3Kaga, K, Nakamura, M, Shinogami, M, Tsuzuku, T, Yamada, K, Shindo, M. Auditory nerve disease of both ears revealed by auditory brainstem responses, electroencephalography and otoacoustic emissions. Scand Audiol 1996;25:233–5
4Konradsson, KS. Bilaterally preserved otoacoustic emissions in four children with profound idiopathic unilateral sensorineural hearing loss. Audiology 1996;31:217–27
5Sheykholeslami, K, Kaga, K, Murofushi, T, Hughes, DW. Vestibular function in auditory neuropathy. Acta Otolaryngol 2000;120:849–54
6Fujikawa, S, Starr, A. Vestibular neuropathy accompanying auditory and peripheral neuropathies. Arch Otolaryngol Head Neck Surg 2000;126:1453–6
7Starr, A, Michalewski, HJ, Zeng, FG, Fujikawa-Brooks, S, Linthicum, F, Kim, CS et al. Pathology and physiology of auditory neuropathy with a novel mutation in the MPZ gene (Tyr145- > Ser). Brain 2003;126:1604–19
8Abdel-Nasser, AA, Elkhayat, NM, Khalil, SH, Mahmoud, LH. Audio-vestibular and neurological correlates in patients with auditory and peripheral neuropathy. Egyptian J Neurol Psych Neurosurg 2006;43:253–67
9Sheykholeslami, K, Schmerber, S, Kermany, MH, Kaga, K. Sacculo-collic pathway dysfunction accompanying auditory neuropathy: case report. Acta Otolaryngol 2005;125:786–91
10Babin, RW, Liu, C, Aschenbrener, C. Histopathology of sensory deafness in neurosarcoidosis. Ann Otol Rhinol Laryngol 1984;93:389–93
11von Brevern, M, Lempert, T, Bronstein, AM, Kocen, R.Selective vestibular damage in neurosarcoidosis. Ann Neurol 1997;42:117–20
12Frohman, EM, Tusa, R, Mark, AS, Comblath, DR. Vestibular dysfunction in chronic inflammatory demyelinating polyneuropathy. Ann Neurol 1996;39:529–35
13Kaga, K. Auditory nerve disease, new classification: auditory and vestibular neuropathy. In: Kaga, K, Starr, A, eds. Neuropathy of the auditory and vestibular eighth cranial nerves. Hicom/Japan: Springer Press, 2009;1320
14Mizutari, K, Matsunaga, T, Inoue, Y, Kaneko, H, Yagi, H, Namba, K et al. Vestibular dysfunction in a Japanese patient with mutation in the gene OPA1. J Neurosci 2010;293:23–8
15Kumar, K, Singh, NK, Bharti, AK, Sinha, SK, Barman, A. Vestibular evoked myogenic potential as a tool to identify vestibular involvement in auditory neuropathy. Asia Pacific Journal of Speech Language and Hearing 2007;10:181–7
16Sazgar, AA, Yazdani, N, Rezazadeh, N, Yazdi, AK. Vestibular evoked myogenic potential (VEMP) in patients with auditory neuropathy: auditory neuropathy or audiovestibular neuropathy? Acta Otolaryngol 2010;130:1130–4


Vestibular test findings in individuals with auditory neuropathy: review

  • S K Sinha (a1), A Barman (a1), N K Singh (a1), G Rajeshwari (a2) and R Sharanya (a1)...


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