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Use of narrow-band imaging in detection of nasopharyngeal carcinoma

Published online by Cambridge University Press:  02 January 2013

J F Thong ,
D Loke ,
R Karumathil Sivasankarannair  and
P Mok
J F Thong*
Affiliation:
Department of Otorhinolaryngology-Head and Neck Surgery, Khoo Teck Puat Hospital, Singapore
D Loke
Affiliation:
Department of Otorhinolaryngology-Head and Neck Surgery, Khoo Teck Puat Hospital, Singapore
R Karumathil Sivasankarannair
Affiliation:
Department of Otorhinolaryngology-Head and Neck Surgery, Khoo Teck Puat Hospital, Singapore
P Mok
Affiliation:
Department of Otorhinolaryngology-Head and Neck Surgery, Khoo Teck Puat Hospital, Singapore
*
Address for correspondence: Dr Jiun Fong Thong, Department of Otorhinolaryngology-Head and Neck Surgery, Khoo Teck Puat Hospital, 90 Yishun Central, Singapore768828 E-mail: jiunfong@yahoo.com
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Abstract

Aim:

To compare narrow-band images of nasopharyngeal carcinoma with those of normal adenoidal tissue.

Method:

Patients with a nasopharyngeal mass were evaluated using both conventional white light and narrow-band light. Biopsies were performed and Epstein–Barr viral serology was tested for all patients.

Results:

Thirty consecutive patients were recruited. Twenty-one patients had normal adenoidal tissue and seven had nasopharyngeal carcinoma. One patient with papillary adenocarcinoma was excluded. The features of narrow-band imaging in normal adenoidal tissue were: (1) a regularly arranged follicular pattern, and (2) each ‘follicle’ comprising a pale centre with surrounding dark periphery. The features of narrow-band imaging in nasopharyngeal carcinoma were: (1) absence of surface patterns (n = 7), and/or (2) ‘reverse’, haphazard follicular pattern comprising a dark brown centre and pale periphery (n = 3).

Conclusion:

Narrow-band imaging of the surface of adenoidal tissue and nasopharyngeal carcinoma appears to identify distinct, characteristic features as described. Narrow-band imaging may be a useful adjunct in differentiating normal adenoidal tissue from malignancy. Further studies are needed to evaluate its diagnostic accuracy.

Keywords

NasopharynxEndoscopyAdenoidsImaging, DiagnosticNasopharyngeal CarcinomaDiagnosis
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 127 , Issue 2 , February 2013 , pp. 163 - 169
Copyright
Copyright © JLO (1984) Limited 2013

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