Skip to main content Accessibility help

The use of Acyclovir in Ramsay Hunt Syndrome

  • F. W. Stafford (a1) and A. R. Welch (a1)


Acyclovir is a specific anti-viral agent which has been used in the treatment of the Ramsay Hunt Syndrome with encouraging results. To our knowledge, no previous study has been published utilizing this treatment. A discussion is also undertaken of the underlying pathology and prognosis of the Ramsay Hunt Syndrome, with a summary of those cases in which Acyclovir was prescribed.


Corresponding author

Andrew Welch, F.R.C.S., Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne. NE1 4LP.


Hide All
Aleksic, S. N., Budzilovich, G. N. and Lieberman, A. N. (1973) Herpes Zoster Oticus and Facial Paralysis (Ramsay-Hunt Syndrome). Clinico-Pathological Study and Review of Literature. Journal of the Neurological Sciences, 20: 149159.
Blackley, B., Friedmann, I. and Wright, I. (1967) Herpes Zoster Auris Associated with Facial Nerve Palsy and Auditory Nerve Symptoms. Acta Otolaryngolologica (Stockholm), 63: 533550.
Bremond, G., Garcin, M., Magnan, J., Pech-Gourg, F. and Acotto, J. (1978) Effects of Herpes Zoster Virus on the Facial Nerve. Annales d'Otolaryngologic (Paris), 95: 240248.
Crabtree, J. A. (1968) Herpes Zoster Oticus. Laryngoscope, 78: 18531878.
Denny-Brown, D., Adams, R. D. and Fitzgerald, P. J. (1944) Pathological Features of Herpes Zoster, a Note on Geniculate Herpes. Archives of Neurology and Psychiatry (Chicago), 51: 216231.
Djupesland, G., Berdal, P., Johannessen, T., Degre, M., Stien, R. and Skrede, S. (1976) Viral infection as a Cause of Acute Peripheral Facial Palsy. Archives of Otolaryngology, 102: 403406.
Elion, G. B., Furman, P. A., Fyfe, J. A., de Miranda, P., Beauchamp, L. and Shaeffer, H. J. (1977) Selectivity of Action of an Anti-Herpetic Agent 9-(2-hydroxyethoxy-methyl) Guanine. Proceedings of the National Academy of Science (U. S. A.), 74: 57165720.
Fleury, P., Basset, J. -M. and Compere, J. -F. (1978) Idiopathic Facial Paralysis and Facial Paralysis due to Herpes Zoster. Revue Laryngologie, Otologie et Rhinologie (Bordeaux), 99: 307322.
Guldberg-Moller, J., Olsen, S. and Kettel, K. (1959) Histopathology of the Facial Nerve in Herpes Zoster Oticus. Archives of Otolaryngology, 69: 266275.
Hunt, J. Ramsey (1907) On Herpetic Inflammation of the Geniculate Ganglion—A New Syndrome and Its Complications. Journal of Nervous and Mental Disease, 34: 7396.
Jones, B. R. (1979) Efficacy of Acycloguanosine Against Herpes Simplex Corneal Ulcers. Lancet 1: 243244.
Mair, I. and Flugsrud, L. B. (1976) Peripheral Facial Palsy and Herpes Zoster Infection. Journal of Laryngology and Otology, 90: 373379.
Mitchell, C. D., Bean, B., Gentry, S. R., Groth, K. E., Boen, J. R. and Balfour, H. H. Jr. (1981) Ayclovir Therapy for Mucocutaneous Herpes Simplex Infections in the Immunosuppressed Patient. Lancet, 1: 13891392.
Nilsen, A. E. (1982) Efficacy of Oral Acyclovir in the Treatment of Initial and Recurrent Genital Herpes. Lancet, 2: 571573.
Payten, R. J. and Dawes, J. D. K. (1972) Herpes Zoster of the Head and Neck. Journal of Laryngology and Otology, 86: 10311055.
Saral, R., Burns, W. H., Laskin, O. L., Santos, G. W. and Leitman, P. S. (1981) Acyclovir Prophylaxis of Herpes Simplex Virus Infection. New England Journal of Medicine, 305: 6367.
Skoldenberg, B. (1984) Acyclovir Versus Viderabine in Herpes Simplex Encephalitis. Lancet, 2: 707711.
Taverner, D. (1965) Electrodiagnosis in Facial Palsy. Archives of Otolaryngology, 81: 470477.
Taverner, D. (1968) The Management of Facial Palsy. Journal of Laryngology and Otology, 82: 585590.
Timbury, M. C. (1982) Acyclovir. British Medical Journal, 285: 12231224.

The use of Acyclovir in Ramsay Hunt Syndrome

  • F. W. Stafford (a1) and A. R. Welch (a1)


Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed