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Tumours of the nose and maxillary sinus. Ten year survey from Kenya

Published online by Cambridge University Press:  29 June 2007

B. Bjerregaard*
Affiliation:
Copenhagen, Denmark
C. A. Okoth-Olende
Affiliation:
Copenhagen, Denmark
D. Gatei
Affiliation:
Copenhagen, Denmark
I. S. Bal
Affiliation:
Copenhagen, Denmark
H. Jensen
Affiliation:
Copenhagen, Denmark
*
Dr Beth Bjerregaard, Department of Pathology, Herlev Hospital, University of Copenhagen, DK-2730 Herlev, Denmark.

Abstract

Between 1976–1985,127 cases of malignant tumours of the nose and maxillary sinus were seen at the Department of Human Pathology, Kenyatta National Hospital, Nairobi, Kenya. Cancer of the nose and maxillary sinus was a common diagnosis accounting for 0.8 per cent of all malignancies. Despite this, the incidence was low probably because the rural Kenyans have difficulty in gaining access to the oncology facilities in Nairobi. Incidence rates standardized to world population per 100,000 persons–years were 0.16 for males and 0.12 for females.

Clinical information showed that malignancy should be expected in patients with swelling of thecheek and involvement of the orbit. Compared with Denmark the proportion of undifferentiated carcinomas was significantly higher in Kenya. The well known fact that anaplastic carcinoma of the postnasal space is causally associated with the Epstein Barr virus makes it tempting to suggest that anaplastic carcinoma of the nose and maxillary sinus may also be of viral aetiology.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 1992

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References

Batsakis, J. G. (1979) Cancer of the nasal cavity and the paranasal sinuses. In Tumuors of the head and neck. 2nd edition. (Batsakis, J. G., ed.) Williams and Wilkins: Baltimore, p. 177–87.Google Scholar
Baumslag, N., Cincinnati, B. Ch., Keen, P. (1972) Trace elements in soil and plants and antral cancer. Archives of Environmental Health, 25: 2325.CrossRefGoogle ScholarPubMed
Clifford, P. (1960) Malignant disease of the nose and nasal sinuses in East Africa. British Journal of Surgery, 48: 1525.CrossRefGoogle ScholarPubMed
Clifford, P. (1967) Malignant disease of the nasopharynx and paranasal sinuses in Kenya. In Cancer of the nasopharynx. 1st edition. (Muir, C. S., Shanmugaratnam, K., eds.) UICC Monograph Series Vol. 1, Munksgaard, Copenhagen, p. 8294.Google Scholar
Henle, W., Henle, G., Ho, H.-C, Burtin, P., Cachin, Y., Clifford, P., DeSchryver, A., De-The, G., Diehl, V., Klein, G. (1970) Antibodies to Epstein-Barr virus in nasopharyngeal carcinoma, other head and neck neoplasm and control groups. Journal of the National Cancer Institute, 44: 225231.Google ScholarPubMed
Keen, P. (1967) Carcinoma of the antrum in the South African Bantu. In Cancer of the nasopharynx. 1st edition. (Muir, C. S., Shanmugaratnam, K., eds.) UICC Monograph Series Vol. 1, Munksgaard, Copenhagen, p. 95100.Google Scholar
Kenady, D. E. (1986) Cancer of the paranasal sinuses. Surgical Clinics of North America, 66: 119131.CrossRefGoogle ScholarPubMed
Martin, J. A. M. (1967) Disease of the ear, nose and throat in tropical Africa. Journal of Laryngology and Otology, 81: 10791098.CrossRefGoogle ScholarPubMed
Muir, C. S., Nectoux, J. (1980) Descriptive epidemiology of malignant neoplasms of nose, nasal cavities, middle ear and accessory sinuses. Clinical Otolaryngology, 5: 195211.CrossRefGoogle ScholarPubMed
Redmond, C. K., Sass, R. E., Roush, G. C. (1982) Nasal cavity and paranasal sinuses. In Cancer epidemiology and prevention. (Schottenfeld, D., Fraumoni, J. E, eds.) W. B. Saunders, Philadelphia, p. 159235.Google Scholar
Republic of Kenya (1981) Central bureau of statistics. Kenya population census, 1979, Vol. 1, Nairobi.Google Scholar
Sisson, G. A., Becker, S. P. (1981) Cancer of the nasal cavity and paranasal sinuses. In Cancer of the head and neck. 1st Edition. (Suen, J. Y., Myers, R. N., eds.) Churchill Livingstone, New York, p. 242279.Google Scholar
Waterhouse, J., Muir, C., Shanmugaratnam, K., Powell, J. (1982) Cancer incidence in five continents. Vol. IV, Lyon, IARC, Scientific publications no. 42.Google Scholar
WHO (1978) Histological typing of upper respiratory tract tumours. International histological classification of tumours. WHO, Geneva.Google Scholar