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The role of MIBG scintigraphy in the management of a case of metastatic glomus jugulare tumour

Published online by Cambridge University Press:  29 June 2007

E. Nilssen  and
P. J. Wormald
E. Nilssen*
Affiliation:
Department of Otorhinolaryngology, Groote Schuur Hospital, Cape Town, Republic of South Africa
P. J. Wormald
Affiliation:
Department of Otorhinolaryngology, Groote Schuur Hospital, Cape Town, Republic of South Africa
*
Address for correspondence: Dr E. Nilssen, Department of Otorhinolaryngology, Groote Schuur Hospital, Cape Town, Republic of South Africa. Fax: 021 4486461
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Abstract

Glomus jugulare tumours with metastases are rare as the diagnosis of metastases in this condition can be difficult.

In the past this diagnosis has been made on histology of the metastatic lesions which were identified on clinical grounds. This is one of the reasons why there have been only 20 reported cases in the literature up to 1990 (Johnstone et al., 1990). This case report examines the role of meta-iodobenzylguanidine (MIBG) scintigraphy in the diagnosis of metastases. MIBG scintigraphy is an injected radionucleotide isotope scanning technique which is cheap, non-invasive, sensitive as well as being a specific investigation for identifying sites of ectopic neuroendocrine tissue. It may also have a role in the treatment of these tumours.

Keywords

Glomus tumoursMIBG scintigraphy
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 110 , Issue 4 , April 1996 , pp. 373 - 375
Copyright
Copyright © JLO (1984) Limited 1996

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References

Cornford, E. J., Wastie, M. L., Morgan, D. A. (1992) Malignant paraganglioma of the mediastinum: a further diagnostic aid and therapeutic use of radiolabelled MIBG. British Journal of Radiology 65: 75–77.Google Scholar
Jackson, C. G. (1993) Neurotologic skull base surgery for glomus tumors, section III. Diagnosis for treatment planning and treatment options. Laryngoscope 103(11) (suppl. 60) 17–22.CrossRefGoogle Scholar
Johnston, F., Symon, L. (1992) Malignant paraganglioma of the glomus jugulare: a case report. British Journal of Neurosurgery 6: 255–260.Google Scholar
Johnstone, P. A. S., Foss, R. D., Desilets, D. J. (1990) Malignant jugulotympanic paragangliomas. Archives of Pathology and Laboratory Medicine 114: 976–979.Google Scholar
Kwekkeboom, D. J., van Urk, H., Pauw, B. K., Lamberts, S. W., Kooij, P. P., Hoogma, R. P., Krenning, E. P. (1993) Octreotide scintigraphy for the detection of paragangliomas. Journal of Nuclear Medicine 34(6): 873–878.Google ScholarPubMed
Maurea, S., Cuocolo, A., Reynolds, J. C., Tumeh, S. S., Begley, M. G., Linehan, W. M., Norton, J. A., Walther, M. M., Keiser, H. R., Neumann, R. D. (1993) I-131-MIBG scintigraphy in pre-operative and post-operative evaluation of paragangliomas: Comparison with CT and MRI. Journal of Nuclear Medicine 34(2): 173–179.Google Scholar
Rockall, T. A., Watkinson, J. C., Clark, S. E. M., Douek, E. E. (1990) Scintigraphic evaluation of glomus tumours. Journal of Laryngology and Otology 104: 33–36.CrossRefGoogle ScholarPubMed
Rossenwasser, H. (1945) Carotid body tumor of middle ear and mastoid. Archives of Otolaryngology 41: 64–67.CrossRefGoogle Scholar
Smith, A. J., van Essen, L. H., Hollema, H., Muskiet, F. A. J., Piers, D. A. (1984) Meta-I-131-iodobenzylguanidine uptake in a non-secreting paraganglioma. Journal of Nuclear Medicine 25: 984–985.Google Scholar
Taylor, D. M., Alford, B. R., Greenberg, S. D. (1965) Metastases of glomus jugulare tumors. Archives of Otolaryngology 82: 5–13.Google Scholar
Von Gils, A. P., van der Mey, A. G., Hoogma, R. P., Falke, T. T., Moolenaar, A. J., Pauwels, E. K., van Kroonenburgh, M. J. (1990) I-123-MIBG scintigraphy in patients with chemodectomas of the head and neck region. Journal of Nuclear Medicine 31(7): 1147–1155.Google Scholar
Urquhart, A. C., Johnson, J. T., Myers, E. N., Schechter, G. L. (1994) Glomus vagale: Paraganglioma of the vagus nerve. Laryngoscope 104: 440–445.CrossRefGoogle ScholarPubMed