Hostname: page-component-8448b6f56d-xtgtn Total loading time: 0 Render date: 2024-04-24T10:10:36.641Z Has data issue: false hasContentIssue false

Parotid acinic cell carcinoma with undifferentiated spindle cell transformation

Published online by Cambridge University Press:  29 June 2007

Jorge A. Ferreiro*
Affiliation:
Division of Anatomic Pathology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota
Amarjit S. Kochar
Affiliation:
Department of Pathology, St Mary Medical Center, Hobart, Indiana, USA
*
Dr Jorge A. Ferreiro, Division of Anatomic Pathology, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA. Fax: 507-284-1599

Abstract

This report describes a 59-year-old black man who had an acinic cell carcinoma with associated malignant spindle cell transformation in the parotid gland. To the best of our knowledge, a similar lesion in the salivary gland has not been previously reported.

Type
Pathology in Focus
Copyright
Copyright © JLO (1984) Limited 1994

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Abrams, A. M, Cornyn, J., Scofield, H. H., Hansen, L. S. (1965) Acinic cell adenocarcinoma of the major salivary glands: a clinicopathologic study of 77 cases. Cancer 18: 11451162.3.0.CO;2-#>CrossRefGoogle ScholarPubMed
Batsakis, J. G., Chinn, E. K., Weimert, T. A., Work, W. P., Krause, C. J. (1979) Acinic cell carcinoma: a clinicopathologic study of 35 cases. Journal of Laryngology and Otology 93: 325340.CrossRefGoogle ScholarPubMed
Batsakis, J. G., Luna, M. A., El-Naggar, A. K. (1990) Histopathologic grading of salivary gland neoplasms: II. Acinic cell carcinomas. Annals of Otology, Rhinology and Laryngology 99: 929933.CrossRefGoogle ScholarPubMed
Bleiweiss, I. J., Huvos, A. G., Lara, J., Strong, E. W. (1992) Carcinosarcoma of the submandibular salivary gland: immunohistochemical findings. Cancer 69: 20312035.3.0.CO;2-3>CrossRefGoogle ScholarPubMed
Colmenero, C., Patron, M., Sierra, I. (1991) Acinic cell carcinoma of the salivary glands: a review of 20 new cases. Journal of Cranio-Maxillo-Facial Surgery 19: 260266.CrossRefGoogle ScholarPubMed
Ellis, G. L., Corio, R. L. (1983) Acinic cell adenocarcinoma: a clinicopathologic analysis of 294 cases. Cancer 52: 542549.3.0.CO;2-A>CrossRefGoogle ScholarPubMed
El-Naggar, A. K., Batsakis, J. G., Luna, M. A., McLemore, D., Byers, R. M. (1990) DNA flow cytometry of acinic cell carcinomas of major salivary glands. Journal of Laryngology and Otology 104: 410416.CrossRefGoogle ScholarPubMed
Garner, S. L., Robinson, R. A., Maves, M. D., Barnes, C. H. (1989) Salivary gland carcinosarcoma: true malignant mixed tumour. Annals of Otology, Rhinology and Laryngology 98: 611614.CrossRefGoogle Scholar
Lewis, J. E., Olsen, K. D., Weiland, L. H. (1991) Acinic cell carcinoma: clinicopathologic review. Cancer 67: 172179.3.0.CO;2-X>CrossRefGoogle ScholarPubMed
Luna, M. A., Tortoledo, M. E., Ordonez, N. G., Frankenthaler, R. A., Batsakis, J. G. (1991) Primary sarcomas of the major salivary glands. Archives of Otolaryngology, Head and Neck Surgery 117: 302306.CrossRefGoogle ScholarPubMed
Oliveira, P., Fonseca, I., Soares, J. (1992) Acinic cell carcinoma of the salivary glands: a long-term follow-up study of 15 cases. European Journal of Surgical Oncology 18: 715.Google ScholarPubMed
Perzin, K. H., Li Volsi, V. A. (1979) Acinic cell carcinomas arising in salivary glands: a clinicopathologic study. Cancer 44: 14341457.3.0.CO;2-H>CrossRefGoogle ScholarPubMed
Schilling, J. A., Block, B. L., Speigel, J. C. (1989) Synchronous unilateral parotid neoplasms of different histologic types. Head and Neck 11: 179183.CrossRefGoogle ScholarPubMed
Spiro, R. H., Huvos, A. G., Strong, E. W. (1978) Acinic cell carcinoma of salivary origin: a clinicopathologic study of 67 cases. Cancer 41: 924935.3.0.CO;2-L>CrossRefGoogle ScholarPubMed
Stanley, R. J., Weiland, L. H., Olsen, K. D., Pearson, B. W. (1988) Dedifferentiated acinic cell (acinous) carcinoma of the parotid gland. Otolaryngology–Head and Neck Surgery 98: 155161.CrossRefGoogle ScholarPubMed
Stephen, J., Batsakis, J. G., Luna, M. A., von der Heyden, U., Byers, R. M. (1986) True malignant mixed tumours (carcinosarcoma) of salivary glands. Oral Surgery, Oral Medicine, Oral Pathology 61: 597602.CrossRefGoogle ScholarPubMed
Wat, P. J., Strickler, J. G., Myers, J. L., Nordstrom, M. R. (1994) Herpes simplex infection causing acute necrotizing tonsillitis. Mayo Clinic Proceedings 69: 269271.CrossRefGoogle ScholarPubMed