Hostname: page-component-848d4c4894-mwx4w Total loading time: 0 Render date: 2024-07-03T14:24:58.342Z Has data issue: false hasContentIssue false
  • English
  • Français

Non-Hodgkin's lymphoma involving the tonsil: An immunohistochemical study

Published online by Cambridge University Press:  29 June 2007

M. G. Watson  and
J. Crocker
M. G. Watson*
Affiliation:
Birmingham
J. Crocker
Affiliation:
Birmingham
*
M. G. Watson, F.R.C.S., ENT Department, Freeman Hospital. High Heaton. Newcastle-upon-Tyne NE7 7DN.
Get access Rights & Permissions [Opens in a new window]

Abstract

Twenty-one patients with non-Hodgkin's lymphoma involving the palatine tonsil were studied in an attempt to relate pathological data to clinical outcome. Eleven tumours were classified as low-grade and ten as high-grade on morphological criteria. The results of immunohistochemical investigations are presented; all tumours but one were of B-cell origin. None of the pathological factors studied were found to be useful prognostic indicators.

Keywords

Tonsillar neoplasmsLymphomanon-HodgkinsImmunohistochemistry
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 105 , Issue 6 , June 1991 , pp. 445 - 450
Copyright
Copyright © JLO (1984) Limited 1991

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Anonymous (1987) NORs—a new method for the pathologist. Lancet, i: 1413–1414.Google Scholar
Banfi, A., Bonadonna, G., Ricci, S. B., Milani, F., Molinari, R., Monfardini, S., Zucali, R. (1972) Malignant lymphoma of Waldeyer's ring: Natural history with survival after radiotherapy. British Medical Journal, 3: 140–143.CrossRefGoogle ScholarPubMed
Barton, J. H., Osborne, B. M., Butler, J. J., Meoz, R. T., Kong, J., Fuller, L. M., Sullivan, J. A. (1984) Non-Hodgkin's lymphoma of the tonsil. A clinicopathologic study of 65 cases. Cancer, 53: 86–95.3.0.CO;2-E>CrossRefGoogle ScholarPubMed
Brugere, J., Schlienger, M., Gerard-Marchant, R., Tubiana, M., Pouillart, P., Cachin, Y. (1975) Non-Hodgkins malignant lymphoma of upper digestive and respiratory tract: Natural history and results of radiotherapy. British Journal of Cancer, 31 (Supplement II): 435–440.Google Scholar
Cortez, E. A., Mattox, D. C., Holt, G. R., Gates, G. A. (1979) Unilateral tonsillar enlargement. Otolaryngology-Head and Neck Surgery, 87: 707–716.CrossRefGoogle ScholarPubMed
Crocker, J. (1990) Nucleolar organizer regions. In Current Topics in Pathology (Underwood, J. C. E., ed.) Springer-Verlag: Heidelberg, pp 91–147.Google Scholar
Crocker, J., Burnett, D. (1986) Granulocyte markers in histopathology: A review. Journal of Pathology, 150: 77–88.CrossRefGoogle ScholarPubMed
Crocker, J., Burnett, D., Jones, E. L. (1984) Immunohistochemical demonstration of cathepsin B in the macrophages of benign and malignant lymphoid tissue. Journal of Pathology, 142: 87–94.CrossRefGoogle Scholar
Crocker, J., Jenkins, R. (1984) A quantitative study of histiocytic reticulum cells in diffuse and follicular non-Hodgkin's lymphoma. Journal of Clinical Pathology, 37: 1222–1226.CrossRefGoogle Scholar
Crocker, J., Jenkins, R., Campbell, J., Fuggle, W. J., Shah, V. M. (1985) Immunohistochemical demonstration of S-100 protein in salivary gland neoplasms. Journal of Pathology, 146: 115–121.CrossRefGoogle ScholarPubMed
Crocker, J., Nar, P. (1987) Nucleolar organizer regions in lymphomas. Journal of Pathology, 151: 111–118.CrossRefGoogle ScholarPubMed
Crocker, J., Overton, S. P., Smith, P. J. (1988) Type IV collagen in Hodgkin's disease. An immunohistochemical study. American Journal of Clinical Pathology, 89: 57–62.CrossRefGoogle ScholarPubMed
Crocker, J., Skilbeck, N. Q. (1987) Nucleolar organizer region associated proteins in cutaneous melanotic lesions: a quantitative study. Journal of Clinical Pathology, 40: 885–889.CrossRefGoogle Scholar
Crocker, J., Skilbeck, N., Brown, G. M., Bunce, C. (1986) 3-fucosyl-N-acetyllactosamine, an antigen demonstrated by antibody AGF4.48, is present in Reed-Sternberg cells. Journal of Clinical Pathology, 39: 564–568.CrossRefGoogle Scholar
Crocker, J., Smith, P. J. (1984) Immunohistochemical localization of Factor VIII-related antigen in Hodgkin's disease. Journal of Clinical Pathology, 37: 37–44.CrossRefGoogle ScholarPubMed
Hall, P. A., D'Ardenne, A. J., Stansfeld, A. G. (1988a) Paraffin section immunohistochemistry. I. Non-Hodgkin's lymphoma. Histopathology, 13: 149–160.CrossRefGoogle ScholarPubMed
Hall, P. A., D'Ardenne, A. J., Stansfeld, A. G. (1988b) Paraffin section immunohitochemistry. II. Hodgkin's disease and large cell anaplastic (Ki1) lymphoma. Histopathology, 13: 161–170.CrossRefGoogle Scholar
Hockey, M. S., Powell, J., Crocker, J., Fielding, J. W. L. (1987) Primary gastric lymphoma. British Journal of Surgery, 74: 483–487.CrossRefGoogle ScholarPubMed
Jack, A. S., Cunningham, D., Soukop, M., Liddle, C. N., Lee, F. D. (1986) Use of Leu M1 and antiepithelial membrane antigen monoclonal antibodies for diagnosing Hodgkin's disease. Journal of Clinical Pathology, 39: 267–270.CrossRefGoogle ScholarPubMed
Lennert, K. (1978) Malignant lymphomas other than Hodgkin's disease. Springer-Verlag: Berlin.CrossRefGoogle Scholar
Sangster, G., Crocker, J., Nar, P., Leyland, M. J. (1986) Benign and malignant (B-cell) lymphoid aggregates in bone marrow trephines shown by means of an immunogold-silver technique. Journal of Clinical Pathology, 39: 453–457.CrossRefGoogle ScholarPubMed
Taylor, C. R. (1986) Immunomicroscopy: A diagnostic tool for the surgical pathologist. WB Saunders Co., Philadelphia. London.Google Scholar
Tetu, B., Manning, J. T., Ordonez, N. G. (1986) Comparison of monoclonal and polygot antibodies directed against immunoglobulin light and heavy chains in non-Hodgkin's lymphoma. American Journal of Clinical Pathology, 85: 25–31.CrossRefGoogle ScholarPubMed