Skip to main content Accessibility help

Long-term follow up of sudden sensorineural hearing loss patients treated with intratympanic steroids: audiological and quality of life evaluation

  • I Dallan (a1), S Fortunato (a1), A P Casani (a1), E Bernardini (a1), S Sellari-Franceschini (a1), S Berrettini (a2) and A Nacci (a2)...



To evaluate the long-term stability of intratympanic steroids and investigate the ‘real’ impact of sudden sensorineural hearing loss on patients.


A total of 14 patients treated with intratympanic steroids were evaluated by audiometric and vestibular examinations. The modified Glasgow Benefit Inventory was used to evaluate quality of life changes after intratympanic steroid treatment.


There was no significant difference between pure tone average post-intratympanic steroids and at follow up. The general Glasgow Benefit Inventory score was not significantly associated with the presence of tinnitus or dizziness, or with patient age. The change in pure tone average after intratympanic steroid treatment did not correlate with social or physical scores, but correlated strongly with the general Glasgow Benefit Inventory score (p = 0.0023). Intratympanic steroid administration led to a stable improvement in hearing. Quality of life assessment showed that patients can feel satisfaction regardless of the hearing outcome. Patients who regained a social hearing level expressed greater satisfaction than patients without serviceable hearing. Overall, quality of life improvement was not related to hearing improvement.


Sudden sensorineural hearing loss is devastating. Considering the audiological effects alone ignores the ‘human’ perspective. Audiological success can correlate with poor quality of life outcome.


Corresponding author

Address for correspondence: Dr S Fortunato, First ENT Unit, Azienda Ospedaliero-Universitaria Pisana, Via Paradisa, 3, 56126 Pisa, Italy Fax: +39 (0)50 997517 E-mail:


Hide All
1Hughes, GB, Freedman, MA, Haberkamp, TJ, Guay, ME. Sudden sensorineural hearing loss. Otolaryngol Clin North Am 1996;29:393405
2Mattox, DE, Simmons, FB. Natural history of sudden sensorineural hearing loss. Ann Otol Rhinol Laryngol 1977;86:463–80
3Rauch, SD, Halpin, CF, Antonelli, PJ, Babu, S, Carey, JP, Gantz, BJ et al. Oral vs intratympanic corticosteroid therapy for idiopathic sudden sensorineural hearing loss: a randomized trial. JAMA 2011;305:2071–9
4Robinson, K, Gatehouse, S, Browning, GG. Measuring patient benefit from otorhinolaryngological surgery and therapy. Ann Otol Rhinol Laryngol 2006;105:415–22
5Kyrodimos, E, Aidonis, I, Skalimis, A, Sismanis, A. Use of Glasgow Benefit Inventory (GBI) in Meniere's disease managed with intratympanic dexamethasone perfusion: quality of life assessment. Auris Nasus Larynx 2011;38:172–7
6Stachler, RJ, Chandrasekhar, SS, Archer, SM, Rosenfeld, RM, Schwartz, SR, Barrs, DM et al. Clinical practice guideline: sudden hearing loss. Otolaryngol Head Neck Surg 2012;146(suppl3):S1–35
7Carlosson, PI, Hall, M, Lind, KJ, Danermark, B. Quality of life, psychosocial consequences, and audiological rehabilitation after sudden sensorineural hearing loss. Int J Audiol 2011;50:139–44
8Yeo, SW, Lee, DH, Jun, BC, Park, SY, Park, YS. Hearing outcome of sudden sensorineural hearing loss: long-term follow up. Otolaryngol Head Neck Surg 2007;136:221–4
9Vrabec, JT. Effectiveness of intratympanic dexamethasone injection in sudden deafness patients as salvage treatment. Laryngoscope 2005;115:378
10Kallinen, J, Laurikainen, E, Bergroth, L, Grenman, R. A follow up study of patients suffering from sudden sensorineural hearing loss. Acta Otolaryngol 2001;121:818–22
11Furuhashi, A, Matzuda, K, Asahi, K, Nakashima, T. Sudden deafness: long-term follow up and recurrences. Clin Otolaryngol 2002;27:458–63
12Lin, HC, Chao, PZ, Lee, HC. Sudden sensorineural hearing loss increases the risk of stroke: a 5-year follow-up study. Stroke 2008;39:2744–8



Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed