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Lemierre's syndrome associated with consumption coagulopathy and acute renal failure: a case report

  • S Georgopoulos (a1), S Korres (a2), M Riga (a2), D Balatsouras (a3), G Kotsis (a4) and E Ferekidis (a2)...

Abstract

Background:

Acute tonsillitis or pharyngitis may lead to suppurative thrombophlebitis of the internal jugular vein. This complication, also known as Lemierre's syndrome, remains, even nowadays, life threatening, due to dissemination of septic thromboemboli to various organs. Respiratory deficiency and renal impairment are often reported in patients suffering from Lemierre's syndrome.

Case report:

The unusual clinical manifestation of this case involves severe acute renal and respiratory deficiency in addition to microangiopathic consumption coagulopathy in a young patient treated with macrolides five days after the onset of acute tonsillitis.

Conclusion:

The usual causative pathogen, namely Fusobacterium necrophorum, shows a varying sensitivity to macrolides. As a result, the syndrome may present itself in a variety of clinical forms even in patients under treatment with macrolides. A high index of suspicion is therefore crucial for in time prevention of potentially life threatening complications.

Copyright

Corresponding author

Address for correspondence: Maria Riga, 7 Athenas str, 54634 Thessaloniki, Greece. Fax: 0030 210 8136971 E-mail: mariariga@hotmail.com

References

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Keywords

Lemierre's syndrome associated with consumption coagulopathy and acute renal failure: a case report

  • S Georgopoulos (a1), S Korres (a2), M Riga (a2), D Balatsouras (a3), G Kotsis (a4) and E Ferekidis (a2)...

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