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Leishmania braziliensis presenting as a granulomatous lesion of the nasal septum mucosa

  • P. J. F. M. Lohuis (a1), M. M. Lipovsky (a2), A. I. M. Hoepelman, G. J. Hordijk (a1) and E. H. Huizing (a1)...

Abstract

Differential diagnosis of granulomatous lesions of the nasal mucosa is difficult. One of the possible causes is an infection with Leishmania braziliensis as reported in this case. Therefore leishmaniasis should be included in the differential diagnosis of granulomatous lesions of the nasal mucosa in patients who have travelled to endemic areas.

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Copyright

Corresponding author

Address for correspondence: Peter J. F. M. Lohuis, M.D., Department of Otorhinolaryngology, University Hospital Utrecht, P0 Box 85.500, NL-3508 GA Utrecht, The Netherlands.

References

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Grögl, M., Oduola, A. M. J., Cordero, L. D. C., Kyle, D. E. (1989) Leishmania spp.: development of pentostam-resistant clones in vitro by discontinuous drug exposure. Experimental Parasitolology 69(1): 7890.
Lainson, R. (1982) Leishmaniasis. In Handbook of Zoonoses. Section C, Parasitic Zoonoses, Vol. 1, C.R.C. Press, Florida, USA, pp 41103.
Klotz, O., Lindenberg, H. (1923) The pathology of leishmaniasis of the nose. American Journal of Tropical Medicine 3: 117141.
Pearson, R. D., de Quieroz Sousa, A. (1995) Leishmania species. In Principles and Practice of Infectious Disease, 4th Edition, Vol 2, Churchill Livingstone, New York, pp 24282442.
Marsden, P. D. (1986) Mucosal leishmaniasis. Transactions of the Royal Society of Tropical Medicine and Hygiene 80: 859876.
Marsden, P. D. (1994) Mucosal leishmaniasis due to Leishmania braziliensis in Três Braços, Bahia-Brasil. Revista da Sociedade Brasileira de Medicina Tropical 27(2): 93101.
Martinez, J. E., Arias, A. L., Escobar, M. E., Saravia, N. G. (1992) Haemoculture of Leishmania braziliensis in two cases of mucosal leishmaniasis: re-examination of haematogenous dissemination. Transactions of the Royal Society of Tropical Medicine and Hygiene 86: 392394.
Zajtchuk, C. J., Casler, J. D., Netto, E. M., Grogl, M., Neafie, R. C., Hessel, C. R., Vercosa de Magalhaes, A., Marsden, P. D. (1989) Mucosal leishmaniasis in Brasil. Laryngoscope 99: 925939.

Keywords

Leishmania braziliensis presenting as a granulomatous lesion of the nasal septum mucosa

  • P. J. F. M. Lohuis (a1), M. M. Lipovsky (a2), A. I. M. Hoepelman, G. J. Hordijk (a1) and E. H. Huizing (a1)...

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