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Kaposi's sarcoma masquerading as pyogenic granuloma of the nasal mucosa

Published online by Cambridge University Press:  29 June 2007

M. E. Wyatt ,
C. J. Finlayson  and
V. Moore-Gillon
M. E. Wyatt*
Affiliation:
Departments of ENT Surgery, St George's Hospital, London, UK.
C. J. Finlayson
Affiliation:
Departments of Histopathology, St George's Hospital, London, UK.
V. Moore-Gillon
Affiliation:
Departments of ENT Surgery, St George's Hospital, London, UK.
*
Address for correspondence: Miss M. E. Wyatt, F.R.C.S., Royal National Throat, Nose and Ear Hospital, Gray's Inn Road, London WC1X 8DA.
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Abstract

Kaposi's sarcoma (KS) is a neoplastic vascular disorder characterized by multiple reddish blue nodules which, according to the original description (Kaposi, 1872), usually present on the skin of the upper and lower extremities. It is not until the disease progresses that nodules appear on the skin of the head and neck, on mucosal membranes and as visceral lesions. However, with the large increase in the incidence of this tumour associated with the acquired immune deficiency syndrome (AIDS) epidemic, there have been increasing numbers of cases of Kaposi's sarcoma presenting primarily on the skin or mucosa of the head and neck. The most common sites reported are within the oral cavity, particularly on the palate. Other mucosal sites are rare. We present an unusual case where the primary manifestation of the Kaposi's sarcoma was in the nasal mucosa and stress the importance of this diagnosis not being overlooked.

Keywords

Sarcoma, Kaposi'sNose
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 112 , Issue 3 , March 1998 , pp. 280 - 282
Copyright
Copyright © JLO (1984) Limited 1998

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References

Chang, Y., Cesarman, E., Pessin, M. S., Lee, F., Culpepper, J., Knowles, D. M.Moore, P. S. (1994) Identification of herpes virus–like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 266: 1865–1869.CrossRefGoogle Scholar
Conaut, M. A. (1995) Management of human immunodeficiency virus-associated malignancies. Recent Results of Cancer Research 139: 423–432.CrossRefGoogle Scholar
Cox, F. H., Helwig, E. B. (1959) Kaposi's sarcoma. Cancer 12: 289–298.3.0.CO;2-Z>CrossRefGoogle ScholarPubMed
Gnepp, D. R., Chandler, W., Hyams, V. (1984) Primary Kaposi's sarcoma of the head and neck. Annals of Internal Medicine 100: 107–114.Google Scholar
Kaposi, M. (1872) Idiopathic multiple pigmented sarcoma of the skin. Archives of Dermatology and Syphilology 4: 265–273.Google Scholar
Lucente, F. E. (1993) Impact of the acquired immune deficiency syndrome epidemic on the practice of laryngology. Annals of Otology, Rhinology and Laryngology Suppl. 161: 1–24.Google ScholarPubMed
Moore, P. S., Gao, S. -J., Dominguez, G., Cesarman, E., Lungu, O., Knowles, D. M., Garber, R., Pellet, P. E., McGeoch, D. J., Chang, Y. (1996) Primary characterisation of a herpes virus agent associated with Kaposi's sarcoma. Journal of Virology 70: 549–558.Google Scholar
Peterman, T. A., Jaffe, H. W., Friedman–Kien, A. E., Weiss, R. A. (1991) The aetiology of Kaposi's sarcoma. Cancer Surveys 10: 23–37.Google ScholarPubMed
Sperling, R. H.Shapiro, D., Coombs, R. W., Todd, J. A., Herman, S. A., McSherry, G. M., O'Sullivan, M. J., Van-Dyke, R. B., Jiminez, E., Rousioux, , Hynn, P. M., Sullivan, J. C. (1996) Maternal viral load zidovidine treatment and the risk of transfer of HIV-1 from mother to infant. New England Journal of Medicine 335:1621–1629.CrossRefGoogle Scholar
Stafford, N. D., Herdman, R. C. D., Forster, S., Munro, A. J. (1989) Kaposi's sarcoma of the head and neck in patients with AIDS. Journal of Laryngology and Otology 103: 379–382.CrossRefGoogle ScholarPubMed