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Jugular foramen involvement in nasopharyngeal carcinoma

  • V. F. H. Chong (a1) and Y. F. Fan (a1)

Abstract

Nasopharyngeal carcinoma (NPC) may spread posterolaterally with infiltration of the jugular foramen, jugular vein and the cranial nerves IX-XI. Cranial nerve palsies may be evident clinically but the extent of skull base infiltration is best assessed radiologically. Denervation atrophy is well demonstrated by both magnetic resonance imaging (MRI) and computed tomography (CT). Accurate delineation of the lesion is important in prognosis and radiotherapy planning.

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Corresponding author

Address for correspondence: Dr Vincent Chong, Department of Diagnostic Radiology, Singapore General Hospital, Outram Road, Singapore 169608.

References

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Ballantyne, A. J., McCarten, A. B., Ibanez, M. L. (1963) Extension of cancer of the head and neck through peripheral nerves. American Journal Surgery 106: 651667.
Curtin, H. D., Williams, R., Johnson, J. (1984) CT of perineural tumour extension: Pterygopalatine fossa. American Journal of Neuroradiology 5: 731737.
Dodd, D. G., Dolan, P. A., Ballantyne, A. J., Ibanez, M. L., Chau, P. (1970) The dissemination of tumors of the head and neck via the cranial nerves. Radiologic Clinics of North America 8: 445461.
Sham, J. S. T., Cheung, Y. K., Choy, D., Chan, F. L., Leong, L. (1990) Nasopharyngeal carcinoma: CT evaluation of patterns of tumor spread. American Journal of Neuroradiology 12: 265270.

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