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Investigation of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and mean platelet volume in patients with tinnitus

Published online by Cambridge University Press:  15 January 2018

B Ulusoy ,
K Bozdemir ,
M Akyol ,
H İ Mişe ,
A Kutluhan  and
M H Korkmaz
B Ulusoy*
Affiliation:
Department of Otorhinolaryngology, Faculty of Medicine, Selçuk University, Konya, Turkey
K Bozdemir
Affiliation:
Department of Otorhinolaryngology, Faculty of Medicine, Yıldırım Beyazıt University, Ankara, Turkey
M Akyol
Affiliation:
Department of Biostatistics, Faculty of Medicine, Yıldırım Beyazıt University, Ankara, Turkey
H İ Mişe
Affiliation:
Department of Otorhinolaryngology, Kaçkar State Hospital, Rize, Turkey
A Kutluhan
Affiliation:
Department of Otorhinolaryngology, Faculty of Medicine, Yıldırım Beyazıt University, Ankara, Turkey
M H Korkmaz
Affiliation:
Department of Otorhinolaryngology, Faculty of Medicine, Yıldırım Beyazıt University, Ankara, Turkey
*
Address for correspondence: Dr Bülent Ulusoy, Department of Otorhinolaryngology, Faculty of Medicine, Selçuk University, Konya 42075, Turkey Fax: +90 332 241 2184 E-mail: ulusoybulent@hotmail.com
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Abstract

Objective:

This study aimed to evaluate patients with tinnitus in terms of mean platelet volume and platelet distribution width, and to explore neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio, recently reported in the literature as being possible inflammation markers.

Methods:

This study comprised 64 tinnitus patients and 64 age-matched healthy controls. Statistical significance level was accepted as p < 0.05.

Results:

Mean platelet volume (t = 3.245, p = 0.002) and platelet distribution width (Z = 3.945, p < 0.001) were significantly higher in the patient group than the control group.

Conclusion:

The results suggest that a prothrombotic condition might play a role in the pathophysiology of tinnitus.

Keywords

Mean Platelet VolumeTinnitusClinical MarkerInflammationThrombosis
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 132 , Issue 2 , February 2018 , pp. 129 - 132
Copyright
Copyright © JLO (1984) Limited 2018 

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