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Intranasal myopericytoma. A tumour with perivascular myoid differentiation: the changing nomenclature for haemangiopericytoma

  • T Wilson (a1), H B Hellquist (a2), S Ray (a3) and J Pickles (a3)

Abstract

We present a case report of a patient who developed a sinonasal myopericytoma treated by surgical excision through a lateral rhinotomy. Some aggressive features on pre-operative computed tomography scanning and the complexity of recent changes in the histological nomenclature for these tumours led to consideration of adjuvant therapy. The close histological relationship between myopericytoma, myofibromatosis, solitary myofibroma and infantile haemangiopericytoma is discussed. This group of lesions constitute a single morphological spectrum with differentiation towards perivascular myoid cells (pericytes). Currently myopericytoma is the most appropriate and accepted term embracing all these entities. A review of the literature has been reassuring in identifying these tumours as benign but with a reasonably high rate of local recurrence (17 per cent). The treatment of choice is surgical excision with further excisions for local recurrence.

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Corresponding author

Address for correspondence: Mr T Wilson, 73 Norfolk Street, Cambridge CB1 2LD, UK. E-mail: t.wilson@doctors.org.uk

References

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1Granter, SR, Badizadegan, K, Fletcher, CD. Myofibromatosis in adults, glomangiopericytoma, and myopericytoma: A spectrum of tumors showing perivascular myoid differentiation. Am J Surg Pathol 1998;22:513–25
2Calonje, E, Fletcher, CDM. Tumors of blood vessels and lymphatics. In: Fletcher, CDMDiagnostic histopathology of tumors, 2nd edn. London: Edinburgh, New York, Churchill Livingstone, 2000;4586
3Stout, AP, Murray, MR. Hemangiopericytoma: a vascular tumor featuring Zimmermann's pericytes. Ann Surg 1942;116:2633
4Requena, L, Kutzner, H, Hugel, H, Rutten, A, Furio, V. Cutaneous adult myofibroma: a vascular neoplasm. J Cutan Pathol 1996;23:445–57
5Thompson, LD, Miettinen, M, Wenig, BM. Sinonasal-type hemangiopericytoma. A clinicopathologic and immunophenotypic analysis of 104 cases showing perivascular myoid differentiation. Am J Surg Pathol 2003;27:737–49
6Barnes, L. Hemangiopericytoma. In: Barnes, L, ed. Surgical Pathology of the Head and Neck. New York: Marcel Decker, 2002;986–91
7Eichhorn, JH, Dickersin, GR, Bhan, AK, Goodman, ML. Sinonasal hemangiopericytoma. A reassessment with electron microscopy, immunohistochemistry, and long-term follow-up. Am J Surg Pathol 1990;14:856–66
8Backwinkel, KD, Diddams, JA. Hemangiopericytoma. Report of a case and comprehensive review of the literature. Cancer 1970;25:896901
9Mentzel, T, Hugel, H, Kutzner, H. CD34-positive glomus tumor: clinicopathologic and immunohistochemical analysis of six cases with myxoid stromal changes. J Cutan Pathol 2002;29:421–5
10McMenamin, ME, Fletcher, CD. Malignant myopericytoma: expanding the spectrum of tumours with myopericytic differentiation. Histopathology 2002;41:450–60
11Tse, LL, Chan, JK. Sinonasal haemangiopericytoma-like tumour: a sinonasal glomus tumour or a haemangiopericytoma. Histopathology 2001;40:510–17

Keywords

Intranasal myopericytoma. A tumour with perivascular myoid differentiation: the changing nomenclature for haemangiopericytoma

  • T Wilson (a1), H B Hellquist (a2), S Ray (a3) and J Pickles (a3)

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