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Hand-grip strength does not correlate with treatment-related weight loss in patients with head and neck cancer

Published online by Cambridge University Press:  08 July 2015

B Cosway
Affiliation:
Department of Otolaryngology, Freeman Hospital, Newcastle upon Tyne, UK
M Easby
Affiliation:
Department of Dietetics, James Cook University Hospital, Middlesbrough, UK
S Covington
Affiliation:
Department of Dietetics, Sunderland Royal Hospital, UK
I Bowe
Affiliation:
Department of Dietetics, Freeman Hospital, Newcastle upon Tyne, UK
V Paleri*
Affiliation:
Department of Otolaryngology, Freeman Hospital, Newcastle upon Tyne, UK
*
Address for correspondence: Prof Vinidh Paleri, Department of Otolaryngology, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK E-mail: Vinidh.Paleri@newcastle.ac.uk

Abstract

Background:

Hand-grip strength has been shown to be a reliable predictor of health outcomes. However, evidence supporting its use as an indicator of nutritional status is inconsistent. This study investigated its use in monitoring nutritional status in patients with head and neck cancer.

Methods:

A prospective audit of patients treated for head and neck cancer was undertaken at four centres over a three-month period in 2009. Nutritional outcomes were collected at 3, 6 and 12 months, and the data were statistically analysed.

Results:

Data from 114 patients showed that mean weight, but not hand-grip strength, fell significantly at 3, 6 and 12 months post-treatment (p < 0.003 vs p < 0.126).

Conclusion:

A fall in weight does not coincide with a drop in hand-grip strength in patients receiving treatment for head and neck cancer. Hand-grip strength may therefore not be of benefit in the nutritional assessment of these patients and should not be part of routine assessment.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 2015 

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Footnotes

On behalf of the North of England Cancer Network Audit group.

References

1Frisancho, AR. Anthropometric Standards for the Assessment of Growth and Nutritional Status. Ann Arbor: University of Michigan Press, 1990CrossRefGoogle Scholar
2Norman, K, Stobäus, N, Gonzalez, MC, Schulzke, JD, Pirlich, M. Hand grip strength: outcome predictor and marker of nutritional status. Clin Nutr 2011;30:135–42CrossRefGoogle ScholarPubMed
3Daniel, PM, Pratt, OE, Spargo, E. The metabolic homoeostatic role of muscle and its function as a store of protein. Lancet 1977;310:446–8CrossRefGoogle Scholar
4Heymsfield, SB, Arteaga, C, McManus, C, Smith, J, Moffitt, S. Measurement of muscle mass in humans: validity of the 24-hour urinary creatinine method. Am J Clin Nutr 1983;37:478–94CrossRefGoogle ScholarPubMed
5Peng, S, Plank, LD, McCall, JL, Gillanders, LK, McIlroy, K, Gane, EJ. Body composition, muscle function, and energy expenditure in patients with liver cirrhosis: a comprehensive study. Am J Clin Nutr 2007;85:1257–66CrossRefGoogle ScholarPubMed
6Windsor, JA, Hill, GL. Grip strength: a measure of the proportion of protein loss in surgical patients. Br J Surg 1988;75:880–2CrossRefGoogle ScholarPubMed
7Norman, K, Schutz, T, Kemps, M, Josef Lubke, H, Lochs, H, Pirlich, M. The Subjective Global Assessment reliably identifies malnutrition-related muscle dysfunction. Clin Nutr 2005;24:143–50CrossRefGoogle ScholarPubMed
8Chilima, DM, Ismail, SJ. Nutrition and handgrip strength of older adults in rural Malawi. Public Health Nutr 2001;4:1118CrossRefGoogle ScholarPubMed
9Pieterse, S, Manandhar, M, Ismail, S. The association between nutritional status and handgrip strength in older Rwandan refugees. Eur J Clin Nutr 2002;56:933–9CrossRefGoogle ScholarPubMed
10Guo, CB, Zhang, W, Ma, DQ, Zhang, KH, Huang, JQ. Hand grip strength: an indicator of nutritional state and the mix of postoperative complications in patients with oral and maxillofacial cancers. Br J Oral Maxillofac Surg 1996;34:325–7CrossRefGoogle ScholarPubMed
11Klidjian, AM, Foster, KJ, Kammerling, RM, Cooper, A, Karran, SJ. Relation of anthropometric and dynamometric variables to serious postoperative complications. BMJ 1980;281:899901CrossRefGoogle ScholarPubMed
12Webb, AR, Newman, LA, Taylor, M, Keogh, JB. Hand grip dynamometry as a predictor of postoperative complications reappraisal using age standardized grip strengths. JPEN J Parenter Enteral Nutr 1989;13:30–3CrossRefGoogle ScholarPubMed
13Bohannon, RW. Hand-grip dynamometry predicts future outcomes in aging adults. J Geriatr Phys Ther 2008;31:310CrossRefGoogle ScholarPubMed
14Kerr, A, Syddall, HE, Cooper, C, Turner, GF, Briggs, RS, Sayer, AA. Does admission grip strength predict length of stay in hospitalised older patients? Age Ageing 2006;35:82–4CrossRefGoogle ScholarPubMed
15Humphreys, J, de la Maza, P, Hirsch, S, Barrera, G, Gattas, V, Bunout, D. Muscle strength as a predictor of loss of functional status in hospitalized patients. Nutrition 2002;18:616–20CrossRefGoogle ScholarPubMed
16Vecchiarino, P, Bohannon, RW, Ferullo, J, Maljanian, R. Short-term outcomes and their predictors for patients hospitalized with community-acquired pneumonia. Heart Lung 2004;33:301–7CrossRefGoogle ScholarPubMed
17Bohannon, RW, Maljanian, R, Ferullo, J. Mortality and readmission of the elderly one year after hospitalization for pneumonia. Aging Clin Exp Res 2004;16:22–5CrossRefGoogle ScholarPubMed
18Rantanen, T, Avlund, K, Suominen, H, Schroll, M, Frändin, K, Pertti, E. Muscle strength as a predictor of onset of ADL dependence in people aged 75 years. Aging Clin Exp Res 2002;14(3 suppl):1015Google ScholarPubMed
19Roland, N, Paleri, V. Head and Neck Cancer: Multidisciplinary Management Guidelines, 4th edn.London: ENT UK, 2011Google Scholar
20Chandrasekaran, B, Ghosh, A, Prasad, C, Krishnan, K, Chandrasharma, B. Age and anthropometric traits predict handgrip strength in healthy normals. J Hand Microsurg 2010;2:5861CrossRefGoogle ScholarPubMed
21Oken, MM, Creech, RH, Tormey, DC, Horton, J, Davis, TE, McFadden, ET et al. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol 1982;5:649–55CrossRefGoogle ScholarPubMed
22Todorovich, TE, Micklewright, A, eds. A Pocket Guide to Clinical Nutrition, 3rd edn.London: Parenteral and Enteral Nutrition Group of the British Dietetic Association, 2004Google Scholar
23Goodpaster, BH, Park, SW, Harris, TB, Kritchevsky, SB, Nevitt, M, Schwartz, AV et al. The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study. J Gerontol A Biol Sci Med Sci 2006;61:1059–64CrossRefGoogle ScholarPubMed
24Bohannon, RW, Magasi, SR, Bubela, DJ, Wang, YC, Gershon, RC. Grip and knee extension muscle strength reflect a common construct among adults. Muscle Nerve 2012;46:555–8CrossRefGoogle ScholarPubMed
25Norman, K, Stobäus, N, Smoliner, C, Zocher, D, Scheufele, R, Valentini, L et al. Determinants of hand grip strength, knee extension strength and functional status in cancer patients. Clin Nutr 2010;29:586–91CrossRefGoogle ScholarPubMed
26Christie, PM, Hill, GL. Effect of intravenous nutrition on nutrition and function in acute attacks of inflammatory bowel disease. Gastroenterology 1990;99:730–6CrossRefGoogle ScholarPubMed
27Paton, NI, Chua, YK, Earnest, A, Chee, CB. Randomized controlled trial of nutritional supplementation in patients with newly diagnosed tuberculosis and wasting. Am J Clin Nutr 2004;80:460–5CrossRefGoogle ScholarPubMed
28Norman, K, Kirchner, H, Freudenreich, M, Ockenga, J, Lochs, H, Pirlich, M. Three month intervention with protein and energy rich supplements improve muscle function and quality of life in malnourished patients with non-neoplastic gastrointestinal disease: a randomized controlled trial. Clin Nutr 2008;27:4856CrossRefGoogle ScholarPubMed
29Ha, L, Hauge, T, Spenning, AB, Iversen, PO. Individual, nutritional support prevents undernutrition, increases muscle strength and improves QoL among elderly at nutritional risk hospitalized for acute stroke: a randomized, controlled trial. Clin Nutr 2010;29:567–73CrossRefGoogle ScholarPubMed
30Beattie, AH, Prach, AT, Baxter, JP, Pennington, CR. A randomised controlled trial evaluating the use of enteral nutritional supplements postoperatively in malnourished surgical patients. Gut 2000;46:813–18CrossRefGoogle ScholarPubMed
31Edington, J, Barnes, R, Bryan, F, Dupree, E, Frost, G, Hickson, M et al. A prospective randomised controlled trial of nutritional supplementation in malnourished elderly in the community: clinical and health economic outcomes. Clin Nutr 2004;23:195204CrossRefGoogle ScholarPubMed
32Price, R, Daly, F, Pennington, CR, McMurdo, ME. Nutritional supplementation of very old people at hospital discharge increases muscle strength: a randomised controlled trial. Gerontology 2005;51:179–85CrossRefGoogle ScholarPubMed
33Smoliner, C, Norman, K, Scheufele, R, Hartig, W, Pirlich, M, Lochs, H. Effects of food fortification on nutritional and functional status in frail elderly nursing home residents at risk of malnutrition. Nutrition 2008;24:1139–44CrossRefGoogle ScholarPubMed
34Milne, AC, Avenell, A, Potter, J. Meta-analysis: protein and energy supplementation in older people. Ann Intern Med 2006;144:3748. Erratum in: Ann Intern Med 2006;144:538CrossRefGoogle ScholarPubMed
35Lønbro, S, Dalgas, U, Primdahl, H, Overgaard, J, Overgaard, K. Feasibility and efficacy of progressive resistance training and dietary supplements in radiotherapy treated head and neck cancer patients–the DAHANCA 25A study. Acta Oncol 2013;52:310–18CrossRefGoogle ScholarPubMed
36Todorovich, TE, Micklewright, A, eds. A Pocket Guide to Clinical Nutrition, 4th edn.London: Parenteral and Enteral Nutrition Group of the British Dietetic Association, 2011Google Scholar
37Innes, E. Handgrip strength testing: a review of the literature. Aust Occup Ther J 1999;46:120–40CrossRefGoogle Scholar