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Haemostasis and analgesia with autologous platelet-rich plasma in tonsillectomy

  • M N Chettri (a1), S K Jayagandhi (a2), Y Konyak (a3), P Sobita (a4), M M Singh (a5) and A M Singh (a6)...

Abstract

Objective

A single-centre, single-blinded prospective experimental study was conducted to determine the effectiveness of autologous platelet-rich plasma applied to the tonsillar bed post-operatively in reducing post-operative pain and haemorrhage.

Methods

Platelet-rich plasma, prepared prior to surgery, was applied with calcium gluconate to one randomly chosen tonsillar fossa. Pain and haemorrhage were analysed, using a visual analogue scale and a pre-defined grading scale respectively, four times on the day of surgery at 2-hourly intervals, and thrice on the following day.

Results

The pain score and haemorrhage grade on the test side were lower than on the control side. These findings were statistically significant.

Conclusion

This pilot study, conducted in India, revealed valid positive results for a promising new technology. The manual preparation of platelet-rich plasma could be automated in the future to allow a larger sample size.

Copyright

Corresponding author

Author for correspondence: Dr Mohonish N Chettri, Department of ENT, Sikkim Manipal Institute of Medical Sciences, Level 4 of Central Referral Hospital, Sikkim Manipal Institute of Medical Sciences, Sikkim Manipal University, Gangtok 737102, Sikkim, India E-mail: mohonish@gmail.com

Footnotes

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Dr M N Chettri takes responsibility for the integrity of the content of the paper

Presented at the 66th National Conference of the Association of Otorhinolaryngologists of India, 11 January 2014, Mysore, India.

Footnotes

References

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1McKerrow, WS, Clarke, R, Tonsillectomy. In: Gleeson, M, ed. Scott-Brown's Otorhinolaryngology, Head and Neck Surgery, 7th edn. London: Edward Arnold, 2008;1228–36
2Irakli, I, Fedor, S. Evaluation of hemostatic and analgetic effects of platelet rich plasma in tonsillectomy. Internet J Otorhinolaryngology 2008;7(2)
3Lacci, KM, Dardik, A. Platelet-rich plasma: support for its use in wound healing. Yale J Biol Med 2010;83:19
4Sonnleitner, D, Huemer, P, Sullivan, DY. A simplified technique of producing platelet rich plasma and platelet concentrate for intraoral bone grafting techniques--a technical note. Int J Oral Maxillofac Implants 2000;15:879–82
5Dominijanni, A, Cristofaro, AG, Brescia, A, Giudice, M. Platelet gel in oral and maxillofacial surgery: a single-centre experience. Blood Transfus 2012;10:200–4
6Gardner, MJ, Demetrakopoulos, D, Paul, RK, Pekka, AM. The efficacy of autologous platelet gel in pain control and blood loss in total knee arthroplasty. Int Orthop 2007;31:309–13
7Bernuzzi, G, Tardito, S, Bussolati, O, Adorni, D, Cantarelli, S, Fagnoni, F et al. Platelet gel in the treatment of cutaneous ulcers: the experience of the Immunohaematology and Transfusion Centre of Parma. Blood Transfus 2010;8:237–47
8Sunitha, RV, Naide, EM. Platelet-rich fibrin: evolution of a second generation platelet concentrate. Indian J Dent Res 2008;19:42–610.4103/0970-9290.38931
9Martinez-Gonzalez, JM, Cano-Sanchez, J, Gonzalo-Lafuente, JC, Campo-Trapero, J, Esparza-Gomez, G, Seoane, J. Do ambulatory-use platelet-rich plasma (PRP) concentrates present risks? Med Oral 2002;7:375–90
10Prkachin, KM, Solomon, PE, Ross, J. Underestimation of pain by health-care providers: towards a model of the process of inferring pain in others. Can J Nurs Res 2007;39:88106
11Semenov, FV, Iakobashvili, II. Usage of platelet-enriched plasma as hemostatic and analgenic medication in tonsillectomy [in Russian]. Vestn Otorinolaringol 2007;6:4850
12Sidman, JD, Lander, TA, Finkelstein, M. Platelet-rich plasma for pediatric tonsillectomy patients. Laryngoscope 2008;118:1765–7

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