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The great mimicker: a rare case of head and neck inflammatory pseudotumour in the presence of human immunodeficiency virus

  • H Ramotar (a1), L Cheung (a1) and L Pitkin (a2)

Abstract

Background:

Inflammatory pseudotumours of the head and neck are rare. A connection has been made between inflammatory pseudotumours and human immunodeficiency virus positivity.

Case report:

This paper reports a case of an inflammatory pseudotumour presenting with a lesion in the left tonsil and left cervical lymph node in a 49-year-old human immunodeficiency virus positive patient. A histological diagnosis was obtained after biopsy and serial radiological imaging.

Conclusion:

Diagnostic uncertainties can lead to unnecessary surgery. It is important to recognise the clinical, radiological and histological indicators of an inflammatory pseudotumour to enable a timely diagnosis and arrange appropriate treatment. In patients with co-morbidities causing immunocompromise, the potential diagnosis of an inflammatory pseudotumour should be considered. This is especially the case in human immunodeficiency virus patients, as inflammatory pseudotumours have been associated with immune reconstitution inflammatory syndrome, which can manifest up to several years after the initiation of, or change in, antiretroviral therapies.

Copyright

Corresponding author

Address for correspondence: Dr Haripriya Ramotar, 38 Leith Road, Wood Green, London N22 5QA, UK E-mail: p_ramotar@hotmail.com

Footnotes

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Presented at the 148th Semon Club meeting, 17 November 2014, London, UK.

Footnotes

References

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9Wang, C, Silverberg, M, Abrams, D. Non-AIDS-defining malignancies in the HIV-infected population. Curr Infect Dis Rep 2014;16:406
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11New York State Department of Health AIDS Institute. Immune Reconstitution Inflammatory Syndrome (IRIS) in HIV-Infected Patients. In: http://cdn.hivguidelines.org/wp-content/uploads/2009/08/IMMUNE-RECONSTITUTION-INFLAMMATORY.pdf [6 September 2014]

Keywords

The great mimicker: a rare case of head and neck inflammatory pseudotumour in the presence of human immunodeficiency virus

  • H Ramotar (a1), L Cheung (a1) and L Pitkin (a2)

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