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Evaluation of serum ischaemia-modified albumin levels in patients with Bell's palsy

Published online by Cambridge University Press:  22 August 2019

A E Göker ,
M H Alagöz ,
G Güntaş ,
A Baskadem Yilmazer ,
G Berkiten ,
B Tutar ,
ME Ekincioglu ,
M F Akgun ,
Y Uyar  and
E Ozdemir
A E Göker*
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, University of Health Sciences, Okmeydani Training and Research Hospital, Istanbul, Turkey
M H Alagöz
Affiliation:
Department of Biochemistry, University of Health Sciences, Okmeydani Training and Research Hospital, Istanbul, Turkey
G Güntaş
Affiliation:
School of Health, Kirklareli University, Kirklareli, Turkey
A Baskadem Yilmazer
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, University of Health Sciences, Okmeydani Training and Research Hospital, Istanbul, Turkey
G Berkiten
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, University of Health Sciences, Okmeydani Training and Research Hospital, Istanbul, Turkey
B Tutar
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, University of Health Sciences, Okmeydani Training and Research Hospital, Istanbul, Turkey
ME Ekincioglu
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, University of Health Sciences, Okmeydani Training and Research Hospital, Istanbul, Turkey
M F Akgun
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, University of Health Sciences, Okmeydani Training and Research Hospital, Istanbul, Turkey
Y Uyar
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, University of Health Sciences, Okmeydani Training and Research Hospital, Istanbul, Turkey
E Ozdemir
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, University of Health Sciences, Okmeydani Training and Research Hospital, Istanbul, Turkey
*
Author for correspondence: Dr Ayşe Enise Göker, Department of Otorhinolaryngology – Head and Neck Surgery, University of Health Sciences, Okmeydani Training and Research Hospital, Istanbul, Turkey E-mail: ayseenise@hotmail.com
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Abstract

Objective

This prospective study aimed to evaluate the relationship between serum ischaemia-modified albumin levels and Bell's palsy severity.

Methods

The study included 30 patients diagnosed with Bell's palsy and 30 healthy individuals. The patients were separated into three disease severity groups (grades 2, 3 and 4) according to House–Brackmann classification. Blood samples were collected from all participants and the results compared between groups.

Results

Significant differences in serum ischaemia-modified albumin were found between the study and control groups (p < 0.001); values were significantly higher in the study group than in the control group.

Conclusion

The significantly higher levels of serum ischaemia-modified albumin in the study group suggest that Bell's palsy pathogenesis is associated with oxidative stress.

Keywords

Facial NerveBell PalsyIschemia-Modified Albumin
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 133 , Issue 9 , September 2019 , pp. 810 - 813
Copyright
Copyright © JLO (1984) Limited, 2019 

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Footnotes

Dr A E Göker takes responsibility for the integrity of the content of the paper

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