Skip to main content Accessibility help
×
Home

Endoscopic resection of malignant sinonasal tumours with or without chemotherapy and radiotherapy

  • I Tojima (a1), T Ogawa (a1), H Kouzaki (a1), S Seno (a1), M Shibayama (a1) and T Shimizu (a1)...

Abstract

Objective:

An increasing number of transnasal endoscopic surgical procedures are being performed, and these procedures are now also utilised in the management of malignant sinonasal tumours. This study aimed to evaluate the outcome of endoscopic resection of sinonasal malignancies, with or without chemotherapy and radiotherapy.

Methods:

Between 2000 and 2009, six patients with sinonasal malignancies (diagnosed on pre-operative biopsy) underwent endoscopic resection at our hospital. The histopathological diagnoses varied and included squamous cell carcinoma, olfactory neuroblastoma, chordoma, extramedullary plasmacytoma and haemangiopericytoma.

Results:

Surgical resection was combined with chemotherapy and/or radiotherapy in four cases. The mean follow-up period was 43 months. One patient suffered local recurrence of chordoma, 84 months after the first operation, but this was successfully treated with proton beam radiotherapy.

Conclusion:

These results suggest that endoscopic resection may be a valid alternative to conventional resection in selected cases of malignant sinonasal tumour.

Copyright

Corresponding author

Address for correspondence: Dr Ichiro Tojima, Department of Otorhinolaryngology, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, Shiga 520-2192, Japan Fax: +81 (0)77 548 2783 E-mail: itirotz@hotmail.com

References

Hide All
1Seno, S, Ogawa, T, Shibayama, M, Ogawa, F, Fukui, J, Owaki, S et al. Endoscopic sinus surgery for the odontogenic maxillary cysts. Rhinology 2009;47:305–9
2Seno, S, Arikata, M, Sakurai, H, Owaki, S, Fukui, J, Suzuki, M et al. Endoscopic ligation of the sphenopalatine artery and the maxillary artery for the treatment of intractable posterior epistaxis. Am J Rhinol Allergy 2009;23:197–9
3Stammberger, H, Anderhuber, W, Walch, C, Papaefthymiou, G. Possibilities and limitations of endoscopic management of nasal and paranasal sinus malignancies. Acta Otorhinolaryngol Belg 1999;53:199205
4Roh, HJ, Batra, PS, Citardi, MJ, Lee, J, Bolger, WE, Lanza, DC. Endoscopic resection of sinonasal malignancies: a preliminary report. Am J Rhinol 2004;18:239–46
5Nicolai, P, Battaglia, P, Bignami, M, Bolzoni, A, Delu, G, Khrais, T et al. Endoscopic surgery for malignant tumors of the sinonasal tract and adjacent skull base: a 10-year experience. Am J Rhinol 2008;22:308–16
6Nicolai, P, Castelnuovo, P, Lombardi, D, Battaglia, P, Bignami, M, Pianta, L et al. Role of endoscopic surgery in the management of selected malignant epithelial neoplasms of the naso-ethmoidal complex. Head Neck 2007;29:1075–82
7Lund, V, Howard, DJ, Wei, WI. Endoscopic resection of malignant tumors of the nose and sinuses. Am J Rhinol 2007;21:8994
8Hanna, E, DeMonte, F, Ibrahim, S, Roberts, D, Levine, N, Kupferman, M. Endoscopic resection of sinonasal cancers with and without craniotomy: oncologic results. Arch Otolaryngol Head Neck Surg 2009;135:1219–24
9Kühn, UM, Mann, WJ, Amedee, RG. Endonasal approach for nasal and paranasal sinus tumor removal. ORL J Otorhinolaryngol Relat Spec 2001;63:366–71
10Podboj, J, Smid, L. Endoscopic surgery with curative intent for malignant tumors of the nose and paranasal sinuses. Eur J Surg Oncol 2007;33:1081–6
11Batra, PS, Citardi, MJ, Worley, S, Lee, J, Lanza, DC. Resection of anterior skull base tumors: comparison of combined traditional and endoscopic techniques. Am J Rhinol 2005;19:521–8
12Luong, A, Citardi, MJ, Batra, PS. Management of sinonasal malignant neoplasms: defining the role of endoscopy. Am J Rhinol Allergy 2010;24:150–5
13Villaret, AB, Yakirevitch, A, Bizzoni, A, Bosio, R, Bignami, M, Pistochini, A et al. Endoscopic transnasal craniectomy in the management of selected sinonasal malignancies. Am J Rhinol Allergy 2010;24:60–5
14McCutcheon, IE, Blacklock, JB, Weber, RS, DeMonte, F, Moser, RP, Byers, M et al. Anterior transcranial (craniofacial) resection of tumors of the paranasal sinuses: surgical technique and results. Neurosurgery 1996;38:471–80
15Nishino, H, Miyata, M, Morita, M, Ishikawa, K, Kanazawa, T, Ichimura, K. Combined therapy with conservative surgery, radiotherapy, and regional chemotherapy for maxillary sinus carcinoma. Cancer 2000;89:1925–32

Keywords

Endoscopic resection of malignant sinonasal tumours with or without chemotherapy and radiotherapy

  • I Tojima (a1), T Ogawa (a1), H Kouzaki (a1), S Seno (a1), M Shibayama (a1) and T Shimizu (a1)...

Metrics

Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed