Skip to main content Accessibility help
×
Home

Clofazimin in the treatment of scleroma

  • M. A. Shehata (a1) and A. M. Salama (a1)

Abstract

Scleroma is a chronic progressive granulomatous disease predominantly affecting the mucous membrane of the upper respiratory tract, endemic in temperate and tropical zone countries including Egypt. Many patients in early stages respond to medical treatment while others do not. In these patients an antileprotic agent Clofazimin (Lamprene®) was tried in 76 patients and the therapeutic results are very promising, especially for the early stages of the disease.

Copyright

Corresponding author

Dr Mostafa Shehata, Professor of Otolaryngology, Faculty of Medicine, Alexandria, Egypt

References

Hide All
Botros, G., Hamilton, P. L., Floyed, T. M., Mufti, A. and Imam, A. (1954). Scleroma in Egypt. Annals of Otology, Rhinology and Laryngology, 63: 4: 10311055.
Burnas, D. W. (1968) Recognition of scleroma (Rhinoscleroma). Laryngoscope, 78: 19481957.
El-Hakeem, A., El-Samma, E. and Mossallam, I. A. (1954) Aureomycin therapy in rhinoscleroma. Journal of Laryngology and Otology, 68: 523534.
El-Mofty, A. (1962) Histological examination of scleroma. Annals of Otology, Rhinology and Laryngology, 71: 377381.
Fisher, E. R. and Dimling, C. (1965) Rhinoscleroma-light and electromicroscopic studies. Archives of Pathology, 78: 501512.
Mackay, J. P. (1976) Clofazimin in dermatology. International Journal of Dermatology, 15: 140141.
Muzyka, M. M. and Grubina, K. M. (1972) Problems of the epidemiology of scleroma. Journal of Hygiene Epidemiology, Microbiology and Immunology, 16: 1080.
New, B. G., Weed, L. A., Nicolos, D. R. et al. , (1948) Rhinoscleroma apparently cured with streptomycin. Annals of Otology, Rhinology and Laryngology, 57: 412417.
Reyes, E. (1946) Rhinoscleroma, observations based on study of two hundred cases. Archives of Dermatology and Syphilology, 54: 531537.
Ssali, C. L. K. (1975) The management of rhinoscleroma. Journal of Laryngology and Otology, 89: 9199.
Shehata, M. A., Sallab, R. and Mandour, M. A. (1975) Radiographic study of scleroma. Journal of Laryngology and Otology, 89: 12431261.
Shum, T. K., Whitaker, C. W. and Meyer, P. R. (1982) Clinical update on rhinoscleroma. Laryngoscope, 92: 11491153.
Steinberg, C. M., Clark, W. D. and Galveston, T. X. (1983) Rhinoscleroma a diagnostic challenge. Laryngoscope, 93: 866870.
Zwiefach, E. (1955) Rhinoscleroma. Journal of Laryngology and Otology, 69: 321330.

Clofazimin in the treatment of scleroma

  • M. A. Shehata (a1) and A. M. Salama (a1)

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed