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Aural metastasis from a nasal malignant melanoma: case report with literature review

  • I Khan (a1), S Mohamad (a2), M Shakeel (a1) and M J Jaramillo (a3)



To raise awareness of nasal malignant melanoma, a rare tumour, and to highlight the difficulty associated with its optimum management.


Case report and literature review.

Case report:

A 71-year-old, Caucasian man was diagnosed with malignant melanoma in the right nasal cavity, after presenting with right-sided epistaxis. He underwent endoscopic medial maxillectomy; histological analysis confirmed that the resection margins were clear. However, within six months he re-presented with a metastatic deposit of malignant melanoma in his right external auditory canal, for which he underwent right temporal bone resection. There was no evidence of distant metastasis on radiological studies. Unfortunately, within a month the tumour recurred in the right nasopharynx. A multidisciplinary team decision was made to offer the patient palliative chemoradiotherapy.


Mucosal malignant melanoma of the nose is very rare, and aural metastasis from this primary site has not previously been reported. Optimum management must involve a multidisciplinary team.


Corresponding author

Address for correspondence: Mr Imran Khan, ENT Specialist Registrar, Ward 45, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, Scotland, AB25 2ZN Fax: +44 (0)1224 554569 E-mail:


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1Mucosal melanomas of the head and neck. In: [11 December 2010]
2Grewal, DS, Lele, SY, Mallya, SV, Baser, B, Bahal, NK, Rege, JD. Malignant melanoma of nasopharynx extending to the nose with metastasis in the neck. J Postgrad Med 1994;40:31–3
3Chang, AE, Karnell, LH, Menck, HR. The National Cancer Data Base report on cutaneous and noncutaneous melanoma. A summary of 84,836 cases from the past decade. Cancer 1998;83:1664–78
4Medina, JE, Ferlito, A, Pellitteri, PK, Shaha, AR, Khafif, A, Devaney, KO et al. Current management of mucosal melanoma of the head and neck. J Surg Oncol 2003;83:116–22
5Lund, VJ, Howard, DJ, Harding, L, Wei, WI. Management options and survival in malignant melanomas of the sinonasal mucosa. Laryngoscope 1999;109:208–11
6Narasimhan, K, Kucuk, O, Lin, HS, Heilbrun, LK, Carron, M, Venkatramanamoorthy, R et al. Sinonasal mucosal melanoma: a 13-year experience at a single institution. Skullbase 2009;19:255–62


Aural metastasis from a nasal malignant melanoma: case report with literature review

  • I Khan (a1), S Mohamad (a2), M Shakeel (a1) and M J Jaramillo (a3)


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