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Aspergillosis of the larynx

  • R. Benson-Mitchell (a1), N. Tolley (a1), C. B. Croft (a1) and A. Gallimore (a1)

Abstract

Primary infection of the larynx with Aspergillus spp. is rare. It is more commonly seen as part of a wider infection involving the respiratory system in an immunocompromised host. In noncompromised patients laryngeal aspergillosis may represent colonization rather than invasion requiring no systemic anti-fungal treatment. The diagnosis is important as the presenting symptoms are suggestive of malignant laryngeal disease.

We present a 62-year-old man with a short history of hoarseness. Direct laryngoscopy and biopsy confirmed the diagnosis of aspergillosis. Clinical presentation, diagnosis and the important pathological characteristics of this infection are discussed.

Copyright

Corresponding author

Mr R. Benson-Mitchell, 5 Haven Lodge, Hayes Crescent, London NW11 0DD.

References

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Cunningham, M., Yu, V. L., Turner, J. (1988) Necrotizing otitis externa due to aspergillus in an immunocompetent host. Archives of Otolaryngology-Head and Neck Surgery 114: 554556.
Ferlito, A. (1974) Primary aspergillosis of the larynx. Journal of Laryngology and Otology 88: 12571263.
Rao, P. B. (1969) Aspergillosis of larynx. Journal of Laryngology and Otology 83: 377379.
Washburn, R. G., Kennedy, D. W., Begley, M G. (1988) Chronic fungal sinusitis in apparently normal hosts. Medicine 67: 231247.
Young, R. G., Jennings, A., Bennett, J. E. (1972) Species identification of invasive aspergillosis in man. American Clinical Pathology 58: 554.

Keywords

Aspergillosis of the larynx

  • R. Benson-Mitchell (a1), N. Tolley (a1), C. B. Croft (a1) and A. Gallimore (a1)

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