Hostname: page-component-78c5997874-m6dg7 Total loading time: 0 Render date: 2024-11-01T21:30:17.022Z Has data issue: false hasContentIssue false
  • English
  • Français

Repair of tympanic membrane perforations using hyaluronic acid: An alternative to myringoplasty

Published online by Cambridge University Press:  29 June 2007

Lars-Eric Stenfors
Lars-Eric Stenfors*
Affiliation:
Presented as a poster exhibition at the Fourth International Conference on Recent Advances in Otitis Media, Bal Harbour, Florida, USA1-4 June 1987
*
Prof. Lars-Eric Stenfors, M.D., Ph.D., University of Tromsø, N-9012, Tromsø, Norway.
Get access Rights & Permissions [Opens in a new window]

Abstract

Fifteen dry, small or medium-sized tympanic membrane perforations were treated by local application of 1 per cent hyaluronic acid after excision of the perforation rim. The duration of the perforations ranged from two months to ten years. Fourteen of the perforations were covered within 15±7.4 (S. D.) days and 5 ± 2.4 (S.D.) applications were needed to achieve closure. Hyaluronic acid treatment of dry tympanic membrane perforations not exceeding one quadrant seems to be an alternative to surgical myringoplasty.

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 103 , Issue 1 , January 1989 , pp. 39 - 40
Copyright
Copyright © JLO (1984) Limited 1989

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Boedts, D. (1978) The tympanic epithelium in normal and pathological conditions. Acta Oto-rhino-laryngological belg, 32: 357–360.Google ScholarPubMed
Clawson, J. P. and Litton, W. B. (1971) The healing process of tympanic membrance perforations. Transactions of the American Academy of Ophthalmology and Otolaryngology, 75: 1302–1312.Google Scholar
Miller, D. and Stegmann, R. (1983) ‘Healon’ (sodium hyaluronate). A guide to its use in ophthalmic surgery. New York, John Wiley & Sons.Google Scholar
Reeve, D. R. E. (1977) Repair of large experimental perforations of the tympanic membrance. Journal of Laryngology and Otology, 91: 767–778.CrossRefGoogle Scholar
Reynen, C. J. H. and Kuypers, W. (1971) The healing pattern of drum membrane. Acta Otolaryngologica, Supplement 287.Google Scholar
Salén, B. (1968) Tympanic membrane grafts of full-thickness skin, fascia and cartilage with its perichondrium. An experimental and clinical investigation. Acta Otolaryngologica, Supplement 244.Google ScholarPubMed
Stenfors, L. E., Salén, B. and Winblad, B. (1980) The healing pattern of experimental tympanic membrance perforations. Acta Otolaryngologica, 90: 267–274.CrossRefGoogle Scholar
Stenfors, L. E., Berghem, L., Bloom, G. D., Hellström, S. and Söderberg, O. (1985) Exogenous hyaluronic acid (Healon) accelerates the healing of experimental myringotomies. Auris-Nasus-Larynx (Tokyo), Supplement 1: 217–218.Google ScholarPubMed