Hostname: page-component-848d4c4894-v5vhk Total loading time: 0 Render date: 2024-06-19T02:45:43.332Z Has data issue: false hasContentIssue false
  • English
  • Français

Prognostic value of mean platelet volume on tinnitus

Published online by Cambridge University Press:  14 December 2015

O Kemal ,
T Müderris ,
F Başar ,
G Kutlar  and
F Gül
O Kemal*
Affiliation:
Otolaryngology Department, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey
T Müderris
Affiliation:
Otolaryngology Department, Ankara Atatürk Education and Research Hospital, Turkey
F Başar
Affiliation:
Otolaryngology Department, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey
G Kutlar
Affiliation:
Otolaryngology Department, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey
F Gül
Affiliation:
Otolaryngology Department, Ankara Atatürk Education and Research Hospital, Turkey
*
Address for correspondence: Dr Ozgur Kemal, Mimoza evleri C blok 75/41, Yesildere mah. Alaçam cad., 55200 Atakum, Samsun, Turkey E-mail: drozgurkemal@gmail.com
Get access Rights & Permissions [Opens in a new window]

Abstract

Objective:

This study aimed to determine whether there was any relationship between tinnitus and mean platelet volume.

Methods:

This retrospective study was conducted between January 2013 and January 2014 in Ankara Atatürk Hospital and Ondokuz Mayıs University Hospital, Turkey, on a study group of 86 patients with tinnitus and a control group of 84 healthy subjects. Mean platelet volume was recorded and comparisons were made between the two groups.

Results:

Mean (± standard deviation) platelet volume was 7.67 ± 0.83 μm3 in the study group and 7.28 ± 0.56 μm3 in the control group. There was a statistically significant difference in mean platelet volume between the tinnitus patients and the healthy subjects (p < 0.05).

Conclusion:

The clinical findings indicated that tinnitus patients had a higher mean platelet volume than the healthy control subjects; however, the pathophysiological mechanism remains unclear.

Keywords

Mean Platelet VolumeTinnitusInner Ear
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 130 , Issue 2 , February 2016 , pp. 162 - 165
Copyright
Copyright © JLO (1984) Limited 2015 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1Nemholt, SS, Schmidt, JH, Wedderkopp, N, Baguley, DM. Prevalence of tinnitus and/or hyperacusis in children and adolescents: study protocol for a systematic review. BMJ Open 2015;5:e006649CrossRefGoogle ScholarPubMed
2Liu, F, Han, X, Li, Y, Yu, S. Acupuncture in the treatment of tinnitus: a systematic review and meta-analysis. Eur Arch Otorhinolaryngol 2014. Epub 2014 Oct 25Google ScholarPubMed
3Tunkel, DE, Bauer, CA, Sun, GH, Rosenfeld, RM, Chandrasekhar, SS, Cunningham, ER Jr et al. Clinical practice guideline: tinnitus. Otolaryngol Head Neck Surg 2014;151:S1–40Google ScholarPubMed
4Pinto, PC, Marcelos, CM, Mezzasalma, MA, Osterne, FJ, de Melo Tavares de Lima, MA, Nardi, AE. Tinnitus and its association with psychiatric disorders: systematic review. J Laryngol Otol 2014;128:660–4CrossRefGoogle ScholarPubMed
5Zhang, J. Auditory cortex stimulation to suppress tinnitus: mechanisms and strategies. Hear Res 2013;295:38–57CrossRefGoogle ScholarPubMed
6Chan, Y. Tinnitus: etiology, classification, characteristics, and treatment. Discov Med 2009;8:133–6Google ScholarPubMed
7Eggermont, JJ. Pathophysiology of tinnitus. Prog Brain Res 2007;166:19–35CrossRefGoogle ScholarPubMed
8Frojmovic, MM, Milton, JG. Human platelet size, shape, and related functions in health and disease. Physiol Rev 1982;62:185–261CrossRefGoogle ScholarPubMed
9Sahin, DY, Gur, M, Elbasan, Z, Yıldırım, A, Akıllı, RE, Koyunsever, NY et al. Mean platelet volume associated with aortic distensibility, chronic inflammation, and diabetes in patients with stable coronary artery disease. Clin Appl Thromb Hemost 2014;20:416–21CrossRefGoogle ScholarPubMed
10Kemal, O, Müderris, T, Sevil, E, Kutlar, G. Relation of mean platelet volume and red blood cell distribution width with epistaxis. Laryngoscope 2015;125:788–90CrossRefGoogle ScholarPubMed
11Vizioli, L, Muscari, S, Muscari, A. The relationship of mean platelet volume with the risk and prognosis of cardiovascular diseases. Int J Clin Pract 2009;63:1509–15CrossRefGoogle ScholarPubMed
12Bath, PM, Butterworth, RJ. Platelet size: measurement, physiology and vascular disease. Blood Coagul Fibrinolysis 1996;7:157–61CrossRefGoogle ScholarPubMed
13Papanas, N, Symeonidis, G, Maltezos, E, Mavridis, G, Karavageli, E, Vosnakidis, T et al. Mean platelet volume in patients with type 2 diabetes mellitus. Platelets 2004;15:475–8CrossRefGoogle ScholarPubMed
14Pathansali, R, Smith, N, Bath, P. Altered megakaryocyte-platelet haemostatic axis in hypercholesterolaemia. Platelets 2001;12:292–7CrossRefGoogle ScholarPubMed
15Kario, K, Matsuo, T, Nakao, K. Cigarette smoking increases the mean platelet volume in elderly patients with risk factors for atherosclerosis. Clin Lab Haematol 1992;14:281–7CrossRefGoogle ScholarPubMed
16Coban, E, Ozdogan, M, Yazicioglu, G, Akcit, F. The mean platelet volume in patients with obesity. Int J Clin Pract 2005;59:981–2CrossRefGoogle ScholarPubMed
17Park, Y, Schoene, N, Harris, W. Mean platelet volume as an indicator of platelet activation: methodological issues. Platelets 2002;13:301–6CrossRefGoogle ScholarPubMed
18Boos, CJ, Lip, GY. Assessment of mean platelet volume in coronary artery disease - what does it mean? Thromb Res 2007;120:11–13CrossRefGoogle ScholarPubMed
19Varol, E, Aksoy, F, Ozaydin, M, Erdogan, D, Dogan, A. Relationship between mean platelet volume and mitral annular calcification. Blood Coagul Fibrinolysis 2013;24:189–93CrossRefGoogle ScholarPubMed
20Martin, JF, Trowbridge, EA, Salmon, G, Plumb, J. The biological significance of platelet volume: its relationship to bleeding time, platelet thromboxane B2 production and megakaryocyte nuclear DNA concentration. Thromb Res 1983;32:443–60CrossRefGoogle ScholarPubMed
21Jakubowski, JA, Thompson, CB, Vaillancourt, R, Valeri, CR, Deykin, D. Arachidonic acid metabolism by platelets of differing size. Br J Haematol 1983;53:503–11CrossRefGoogle ScholarPubMed
22Balta, S, Demirkol, S, Yildizoglu, U, Arslan, Z, Unlu, M, Celik, T. Other inflammatory markers ought to be kept in mind when assessing the mean platelet volume in clinical practice. Eur Arch Otorhinolaryngol 2013;270:2373–4CrossRefGoogle ScholarPubMed
23Kemal, Y, Demirağ, G, Ekiz, K, Yücel, I. Mean platelet volume could be a useful biomarker for monitoring epithelial ovarian cancer. J Obstet Gynaecol 2014;34:515–18CrossRefGoogle ScholarPubMed
24Yazici, S, Yazici, M, Erer, B, Calik, Y, Ozhan, H, Ataoglu, S. The platelet indices in patients with rheumatoid arthritis: mean platelet volume reflects disease activity. Platelets 2010;21:122–5CrossRefGoogle ScholarPubMed
25Douda, T, Bures, J, Rejchrt, S, Kopácová, M, Pecka, M, Malý, J. Mean platelet volume (MPV) in Crohn's disease patients [in Czech]. Cas Lek Cesk 2006;145:870–3Google ScholarPubMed
26Kapsoritakis, AN, Koukourakis, MI, Sfiridaki, A, Potamianos, SP, Kosmadaki, MG, Koutroubakis, IE et al. Mean platelet volume: a useful marker of inflammatory bowel disease activity. Am J Gastroenterol 2001;96:776–81CrossRefGoogle ScholarPubMed
27Ulasli, SS, Ozyurek, BA, Yilmaz, EB, Ulubay, G. Mean platelet volume as an inflammatory marker in acute exacerbation of chronic obstructive pulmonary disease. Pol Arch Med Wewn 2012;122:284–90Google ScholarPubMed
28Zareifar, S, Farahmand Far, MR, Golfeshan, F, Cohan, N. Changes in platelet count and mean platelet volume during infectious and inflammatory disease and their correlation with ESR and CRP. J Clin Lab Anal 2014;28:245–8CrossRefGoogle ScholarPubMed
29Sagit, M, Kavugudurmaz, M, Guler, S, Somdas, MA. Impact of mean platelet volume on the occurrence and severity of sudden sensorineural hearing loss. J Laryngol Otol 2013;127:972–6CrossRefGoogle ScholarPubMed
30Ulu, S, Ulu, MS, Ahsen, A, Yucedag, F, Aycicek, A, Celik, S. Increased levels of mean platelet volume: a possible relationship with idiopathic sudden hearing loss. Eur Arch Otorhinolaryngol 2013;270:2875–8CrossRefGoogle ScholarPubMed
31Karli, R, Alacam, H, Unal, R, Kucuk, H, Aksoy, A, Ayhan, E. Mean platelet volume: is it a predictive parameter in the diagnosis of sudden sensorineural hearing loss? Indian J Otolaryngol Head Neck Surg 2013;65:350–3CrossRefGoogle ScholarPubMed
32Bláha, M, Košťál, M, Dršata, J, Chrobok, V, Lánská, M, Zák, P. Does mean platelet volume really increase in sudden sensorial hearing loss? Eur Arch Otorhinolaryngol 2015;272:2575–8CrossRefGoogle ScholarPubMed
33Ma, H, Lin, H, Hu, Y, Li, X, He, W, Jin, X et al. Mean platelet volume in relation to carotid atherosclerosis in normotensive, euglycemic, and normolipidemic Chinese middle-aged and elderly adults. Angiology 2014;65:512–18CrossRefGoogle ScholarPubMed
34Arslan, N, Makay, B, Hızlı, S, Koçyiğit, A, Demircioğlu, F, Tuncel, AS et al. Assessment of atherosclerosis in obese adolescents: positive correlation of mean platelet volume and carotid intima media thickness. J Paediatr Child Health 2013;49:963–8CrossRefGoogle ScholarPubMed
35Li, B, Liu, X, Cao, ZG, Li, Y, Liu, TM, Wang, RT. Elevated mean platelet volume is associated with silent cerebral infarction. Intern Med J 2014;44:653–7CrossRefGoogle ScholarPubMed
36Yüksel Kalkan, G, Gür, M, Baykan, AO, Uçar, H, Elbasan, Z, Şahin, DY et al. Mean platelet volume is associated with aortic intima-media thickness in patients without clinical manifestation of atherosclerotic cardiovascular disease. Anatol J Cardiol 2015;15:753–8CrossRefGoogle ScholarPubMed