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Surgical treatment of hepatic cystic echinococcosis in patients co-infected with HIV/AIDS

  • B. Ran (a1), Y. Shao (a1), Y. Guo (a2), Y. Yimiti (a1), T. Aji (a1), J. Jia (a2), P. Shayiding (a1), T. Jiang (a1), L. Cheng (a1), J. Li (a1) (a3), D.P. McManus (a3), W. Zhang (a1) (a3) and H. Wen (a1)...


Co-infections of cystic echinococcosis (CE) and HIV/AIDS is rare. We report four CE cases that were HIV positive. Three out of the four patients underwent a surgical operation to remove the hydatid cysts in their livers. The operation confirmed that in two of the cases their cysts had ruptured. These patients were given 3 months of albendazole after the operation. Follow-up showed they were remarkably improved in term of their health, although they were still HIV antibody positive 6 months after surgical treatment. Interestingly, the treatment remarkably increased their CD4+ cell population. We showed that surgery is suitable for treating hepatic cystic echinococcosis with HIV/AIDS co-infection.


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Craig, P.S., McManus, D.P., Lightowlers, M.W., Chabalgoity, J.A., Garcia, H.H., Gavidia, C.M., Gilman, R.H., Gonzalez, A.E., Lorca, M., Naquira, C., Nieto, A. & Schantz, P.M. (2007) Prevention and control of cystic echinococcosis. Lancet Infectious Diseases 7, 385394.
Feng, X., Wen, H., Zhang, Z., Chen, X., Ma, X., Zhang, J., Qi, X., Bradshaw, H., Vuitton, D. & Craig, P.S. (2010) Dot immunogold filtration assay (DIGFA) with multiple native antigens for rapid serodiagnosis of human cystic and alveolar echinococcosis. Acta Tropica 113, 114120.
Frider, B., Larrieu, E. & Odriozola, M. (1999) Long-term outcome of asymptomatic liver hydatidosis. Journal of Hepatology 30, 228231.
Javed, A., Kalayarasan, R. & Agarwal, A.K. (2012) Liver hydatid with HIV infection: an association? Journal of Gastrointestinal Surgery 16, 12751277.
McManus, D.P., Zhang, W., Li, J. & Bartley, P.B. (2003) Echinococcosis. Lancet 362, 12951304.
MOH & UNAIDS. (2011) WHO 2011 estimates for the HIV/AIDS epidemic in China. Annual Report of Ministry of Health of People's Republic of China, Joint United Nations Programme on HIV/AIDS and World Health Organization.
Moro, P.L., Gilman, R.H., Verastegui, M., Bern, C., Silva, B. & Bonilla, J.J. (1999) Human hydatidosis in the Central Andes of Peru: evolution of the disease over 3 years. Clinical Infectious Diseases 29, 807812.
Ramos, J.M., Masia, M., Padilla, S., Bernal, E., Martin-Hidalgo, A. & Gutierrez, F. (2007) Fatal infection due to larval cysts of cestodes (neurocysticercosis and hydatid disease) in human immunodeficiency virus (HIV) infected patients in Spain: report of two cases. Scandinavian Journal of Infectious Diseases 39, 719723.
Sailer, M., Soelder, B., Allerberger, F., Zaknun, D., Feichtinger, H. & Gottstein, B. (1997) Alveolar echinococcosis of the liver in a six-year-old girl with acquired immunodeficiency syndrome. Journal of Paediatrics 130, 320323.
Sharma, S.K. & Soneja, M. (2011) HIV and immune reconstitution inflammatory syndrome (IRIS). Indian Journal of Medical Research 134, 866877.
Yuksel, M., Kir, A., Ercan, S., Batirel, H.F. & Baysungur, V. (1997) Correlation between sizes and intracystic pressures of hydatid cysts. European Journal of Cardio-thoracic Surgery 12, 903906.
Zingg, W., Renner-Schneiter, E.C., Pauli-Magnus, C., Renner, E.L., van Overbeck, J., Schlapfer, E., Weber, M., Weber, R., Opravil, M., Gottstein, B. & Speck, R.F. (2004) Alveolar echinococcosis of the liver in an adult with human immunodeficiency virus type-1 infection. Infection 32, 299302.


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