Skip to main content Accessibility help
×
Home

Strongyloides ratti: dissociation of immunological memory of the protection against tissue migrating larvae and intestinal adult worms in mice

  • T. Abe (a1), K. Yoshimura (a1) and Y. Nawa (a2)

Abstract

Immunological memory generated by infection with S. ratti was studied separately in the migratory and intestinal phases in mice. Protection against reinfection in the migratory phase was 96–98% at 2 weeks but significantly decreased to 60% at 12 weeks after the primary infection. However, protection in the intestinal phase was 96% even 12 weeks after the primary infection. Recall of immunity against the intestinal phase persists for longer than that against the migratory phase in mice.

Copyright

References

Hide All
Abe, T., Nawa, Y. (1988a) Worm expulsion and mucosal mast cell response induced by repetitive IL-3 administration in Strongyloides ratti-infected nude mice. Immunology, 63, 181185.
Abe, T. & Nawa, Y. (1988b) Kinetic study of mast-cell growth factor production by lymphocytes during the course of Strongyloides ratti infection in mice. Parasitology Research, 74, 484488.
Bell, R. G., Adams, L. S. & Gerb, J. (1981) Strongyloides ratti: Dissociation of the rat's protective immunity into systemic and intestinal components. Experimental Parasitology, 52, 386395.
Dawkins, H. J. S. & Grove, D. I. (1981) Transfer by serum and cells of resistance to infection with Strongyloides ratti in mice. Immunology, 43, 317322.
Grove, D. I. & Northern, C. (1989) Dissociation of the protective immune response in the mouse to Strongyloides ratti. Journal of Helminthology, 63, 307314.
Haddow, W. J., Moqbel, R. & Wakelin, D. (1984) Transfer of immunity against Strongyloides ratti (Nematoda) using immune spleen cells. Journal of Parasitology, 70, 187189.
Korenaga, M., Nawa, Y., Minori, T. & Tada, I. (1983) Strongyloides ratti: The role of enteral antigenic stimuli by adult worms in the generation of protective immunity in rats. Experimental Parasitology, 55, 358363.
Nawa, Y., Abe, T., Imai, J. & Maruyama, H. (1988) Impaired natural defense of beige (Chediak-Higashi syndrome) mice against tissue-migrating larvae of Strongyloides ratti and its reconstitution by bone marrow cells. Parasite Immunology, 10, 117126.
Tada, I., Mimori, T. & Nakai, M. (1979) Migration route of Strongyloides ratti in albino rats. Japanese Journal of Parasitology, 28, 219227.

Keywords

Strongyloides ratti: dissociation of immunological memory of the protection against tissue migrating larvae and intestinal adult worms in mice

  • T. Abe (a1), K. Yoshimura (a1) and Y. Nawa (a2)

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed.